Pneumococcal capsules and their types: past, present, and future
Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
Enzymatic modifications of exopolysaccharides enhance bacterial persistence
Biofilms are surface-attached communities of bacterial cells embedded in a self-produced
matrix that are found ubiquitously in nature. The biofilm matrix is composed of various …
matrix that are found ubiquitously in nature. The biofilm matrix is composed of various …
Biochemical, genetic, and serological characterization of two capsule subtypes among Streptococcus pneumoniae serotype 20 strains: discovery of a new …
The bacterial pathogen Streptococcus pneumoniae expresses one of over 90 structurally
distinct polysaccharide (PS) capsule serotypes. Prior PS structural analyses of the vaccine …
distinct polysaccharide (PS) capsule serotypes. Prior PS structural analyses of the vaccine …
Bacterial capsules: Occurrence, mechanism, and function
S Gao, W Jin, Y Quan, Y Li, Y Shen, S Yuan… - npj Biofilms and …, 2024 - nature.com
In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …
variety of immune escape mechanisms to enhance their ability to infect the host. The …
Discovery of novel pneumococcal serotype 35D, a natural WciG-deficient variant of serotype 35B
Pneumococcus (Streptococcus pneumoniae) remains a significant cause of morbidity and
mortality, especially among those at the extremes of age. Its capsular polysaccharide is …
mortality, especially among those at the extremes of age. Its capsular polysaccharide is …
Antioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans
SM Lin, CY Baek, JH Jung, WS Kim, HY Song… - Scientific reports, 2020 - nature.com
Deinococcus radiodurans shows extreme resistance to a range of remarkable
environmental stresses. Deinococcal exopolysaccharide (DeinoPol) is a component of the …
environmental stresses. Deinococcal exopolysaccharide (DeinoPol) is a component of the …
Pneumococcal Capsule Synthesis Locus cps as Evolutionary Hotspot with Potential to Generate Novel Serotypes by Recombination
Diversity of the polysaccharide capsule in Streptococcus pneumoniae—main surface
antigen and the target of the currently used pneumococcal vaccines—constitutes a major …
antigen and the target of the currently used pneumococcal vaccines—constitutes a major …
Role of O-acetylation in the immunogenicity of bacterial polysaccharide vaccines
F Berti, R De Ricco, R Rappuoli - Molecules, 2018 - mdpi.com
The incidence of infectious diseases caused by several bacterial pathogens such as
Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis …
Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis …
Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units
MB Oliver, MPG van der Linden, SA Küntzel… - Journal of Biological …, 2013 - ASBMB
Streptococcus pneumoniae is a persistent, opportunistic commensal of the human
nasopharynx and is the leading cause of community-acquired pneumonia. It expresses an …
nasopharynx and is the leading cause of community-acquired pneumonia. It expresses an …
Bacterial surface capsular polysaccharides from Streptococcus pneumoniae: A systematic review on structures, syntheses, and glycoconjugate vaccines
PK Mandal - Carbohydrate Research, 2021 - Elsevier
The polysaccharide capsule of Streptococcus pneumoniae constitutes the outermost surface
structure of the organism and plays a critical role in virulence. The capsule is the target of …
structure of the organism and plays a critical role in virulence. The capsule is the target of …