The impact of the gut microbiota on the reproductive and metabolic endocrine system

X Qi, C Yun, Y Pang, J Qiao - Gut microbes, 2021 - Taylor & Francis
As the gut microbiota exerts various effects on the intestinal milieu which influences distant
organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota …

New insights into the pathogenesis and nonsurgical management of Graves orbitopathy

PN Taylor, L Zhang, RWJ Lee, I Muller… - Nature Reviews …, 2020 - nature.com
Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …

A cause–effect relationship between graves' Disease and the gut microbiome contributes to the thyroid–gut axis: A bidirectional two-sample mendelian randomization …

J Cao, N Wang, Y Luo, C Ma, Z Chen… - Frontiers in …, 2023 - frontiersin.org
Background An association between Graves' disease (GD) and the gut microbiome has
been identified, but the causal effect between them remains unclear. Methods Bidirectional …

Microbiota and thyroid interaction in health and disease

E Fröhlich, R Wahl - Trends in Endocrinology & Metabolism, 2019 - cell.com
The microbiota has been identified as an important factor in health and in a variety of
diseases. An altered microbiota composition increases the prevalence of Hashimoto's …

The relationships between the gut microbiota and its metabolites with thyroid diseases

W Jiang, G Lu, D Gao, Z Lv, D Li - Frontiers in endocrinology, 2022 - frontiersin.org
Emerging studies have provided a preliminary understanding of the thyroid-gut axis,
indicating that intestinal microbiota and its metabolites may act directly or indirectly on the …

Graves' disease

TF Davies, S Andersen, R Latif, Y Nagayama… - Nature reviews Disease …, 2020 - nature.com
Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is
the most common cause of hyperthyroidism and occurs at all ages but especially in women …

Gut microbiome associated with Graves disease and Graves orbitopathy: the INDIGO multicenter European study

F Biscarini, G Masetti, I Muller… - The Journal of …, 2023 - academic.oup.com
Context Gut bacteria can influence host immune responses but little is known about their
role in tolerance-loss mechanisms in Graves disease (GD; hyperthyroidism caused by …

Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection

Q Zhang, J Hu, JW Feng, XT Hu, T Wang, WX Gong… - Genome biology, 2020 - Springer
Background Influenza is a severe respiratory illness that continually threatens global health.
It has been widely known that gut microbiota modulates the host response to protect against …

Gut microbiome and thyroid autoimmunity

C Virili, I Stramazzo, M Centanni - Best Practice & Research Clinical …, 2021 - Elsevier
Intestinal microbiota gained attention due to its pleiotropic effect on intestinal barrier,
nutrients metabolism and on immune system development and functions. Recent evidence …

Microbiota alterations in patients with autoimmune thyroid diseases: a systematic review

N Sawicka-Gutaj, D Gruszczyński, N Zawalna… - International Journal of …, 2022 - mdpi.com
Autoimmune thyroid diseases (AITDs) are chronic autoimmune disorders that cause
impaired immunoregulation, leading to specific immune responses against thyroid antigens …