The lateral line organ is a mechanosensory organ of fish and amphibians that detects
changes in water flow. The lateral line organ of zebrafish has been used as a model for cell …

Background: Damage or destruction of sensory hair cells in the inner ear leads to hearing or
balance deficits that can be debilitating, especially in older adults. Unfortunately, the …

When flying or swimming, animals must adjust their own movement to compensate for
displacements induced by the flow of the surrounding air or water. These flow-induced …

The lateral line sensory system, found in fish and amphibians, is used in prey detection,
predator avoidance and schooling behavior. This system includes cell clusters, called …

Retrograde axonal transport requires an intricate interaction between the dynein motor and
its cargo. What mediates this interaction is largely unknown. Using forward genetics and a …

The asymmetric location of stereociliary bundle (hair bundle) on the apical surface of
mechanosensory hair cells (HCs) dictates the direction in which a given HC can respond to …

Ribbon synapses of the ear, eye and pineal gland contain a unique protein component:
Ribeye. Ribeye consists of a novel aggregation domain spliced to the transcription factor …

Death of mechanosensory cells in the inner ear results in two profound disabilities: hearing
loss and balance disorders. Although mammals lack the capacity to regenerate hair cells …

Hair cells in the inner ear display a characteristic polarization of their apical stereocilia
across the plane of the sensory epithelium. This planar orientation allows coherent …

The zebrafish lateral line is a sensory system used to detect changes in water flow. It is
comprised of clusters of mechanosensory hair cells called neuromasts. The lateral line is …