PLGA: a unique polymer for drug delivery

DN Kapoor, A Bhatia, R Kaur, R Sharma… - Therapeutic …, 2015 - Taylor & Francis
Biodegradable polymers have played an important role in the delivery of drugs in a
controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of the extensively …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Recent developments in natural and synthetic polymeric drug delivery systems used for the treatment of osteoarthritis

M Rahimi, G Charmi, K Matyjaszewski, X Banquy… - Acta biomaterialia, 2021 - Elsevier
Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in
older populations and is expected to be the most dominant cause of disability in the world …

In vitro skin models as a tool in optimization of drug formulation

GE Flaten, Z Palac, A Engesland… - European journal of …, 2015 - Elsevier
Abstract (Trans) dermal drug therapy is gaining increasing importance in the modern drug
development. To fully utilize the potential of this route, it is important to optimize the delivery …

Polymer nanoparticles for smart drug delivery

D Bennet, S Kim - Application of nanotechnology in drug delivery, 2014 - books.google.com
In the recent decades, polymers are widely used as biomaterials due to their favorable
properties such as good biocompatibility, easy design and preparation, a variety of …

Recent advances in PLGA based nanocarriers for drug delivery system: a state of the art review

SR Pardeshi, A Nikam, P Chandak… - … Journal of Polymeric …, 2023 - Taylor & Francis
The biomolecules in the clinical use being delivered by the conventional mode of delivery
often exhibit poor affinity. So, there is a need for a nanomedicine-based approach that could …

Human skin models: From healthy to disease‐mimetic systems; characteristics and applications

T Moniz, SA Costa Lima, S Reis - British journal of …, 2020 - Wiley Online Library
Skin drug delivery is an emerging route in drug development, leading to an urgent need to
understand the behaviour of active pharmaceutical ingredients within the skin. Given, As …

A simple non-invasive approach toward efficient transdermal drug delivery based on biodegradable particulate system

YI Svenskaya, EA Genina… - … applied materials & …, 2019 - ACS Publications
Transdermal administration via skin appendages enables both localized and systemic drug
delivery, as well as minimizes incidental toxicity. However, the design of an appropriate …

Polymeric nanoparticles based on carboxymethyl chitosan in combination with painless microneedle therapy systems for enhancing transdermal insulin delivery

P Zhang, Y Zhang, CG Liu - RSC advances, 2020 - pubs.rsc.org
Biodegradable nanoparticles (NPs) have been frequently used as insulin transdermal
delivery vehicles due to their grand bioavailability, better encapsulation, controlled release …

Progress and Challenges of Topical Delivery Technologies Meditated Drug Therapy for Osteoarthritis

CY Shentu, HB Wang, X Peng, DC Xu… - International Journal …, 2024 - Taylor & Francis
Osteoarthritis (OA) is a degenerative disease commonly seen in middle-aged and elderly
people. Multiple cytokines are involved in the local tissue damage in OA. Currently, non …