Implications of Nef: host cell interactions in viral persistence and progression to AIDS
NJ Arhel, F Kirchhoff - HIV Interactions with Host Cell Proteins, 2009 - Springer
Abstract The HIV and SIV Nef accessory proteins are potent enhancers of viral persistence
and accelerate progression to AIDS in HIV-1-infected patients and non-human primate …
and accelerate progression to AIDS in HIV-1-infected patients and non-human primate …
HIV and the tuberculosis “set point”: how HIV impairs alveolar macrophage responses to tuberculosis and sets the stage for progressive disease
SC Auld, BS Staitieh - Retrovirology, 2020 - Springer
As HIV has fueled a global resurgence of tuberculosis over the last several decades, there is
a growing awareness that HIV-mediated impairments in both innate and adaptive immunity …
a growing awareness that HIV-mediated impairments in both innate and adaptive immunity …
Macrophage internal HIV-1 is protected from neutralizing antibodies
H Koppensteiner, C Banning, C Schneider… - Journal of …, 2012 - Am Soc Microbiol
In macrophages, HIV-1 accumulates in intracellular vesicles designated virus-containing
compartments (VCCs). These might play an important role in the constitution of …
compartments (VCCs). These might play an important role in the constitution of …
Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue
M Schindler, D Rajan, C Banning, P Wimmer… - Retrovirology, 2010 - Springer
Background The human immunodeficiency virus type 1 (HIV-1) Vpu protein degrades CD4
and counteracts a restriction factor termed tetherin (CD317; Bst-2) to enhance virion release …
and counteracts a restriction factor termed tetherin (CD317; Bst-2) to enhance virion release …
Bovine viral diarrhea virus infection affects the expression of proteins related to professional antigen presentation in bovine monocytes
The complete annotation of the cattle genome allows reliable protein identification by
tandem mass spectrometry (MS2) and greatly facilitates proteomics. Previously, we reported …
tandem mass spectrometry (MS2) and greatly facilitates proteomics. Previously, we reported …
Immunoregulatory effects of HIV‐1 Nef protein
MG Quaranta, B Mattioli, L Giordani, M Viora - Biofactors, 2009 - Wiley Online Library
During HIV infection, the perturbation of the adaptive and innate immune responses
contributes to the progressive immunosuppression leading to an increased susceptibility to …
contributes to the progressive immunosuppression leading to an increased susceptibility to …
Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human …
M Schindler, D Rajan, A Specht, C Ritter… - Journal of …, 2007 - Am Soc Microbiol
Interaction of the human immunodeficiency virus type 1 (HIV-1) Nef protein with p21-
activated kinase 2 (PAK2) has been proposed to play a role in T-cell activation, viral …
activated kinase 2 (PAK2) has been proposed to play a role in T-cell activation, viral …
Low prevalence of transmitted genetic drug resistance in a cohort of HIV infected naive patients entering antiretroviral treatment programs at two sites in northern …
Infection with drug resistant viruses influences the outcome of antiretroviral therapy (ART).
This study was carried out to determine the transmitted genetic drug resistance profile in a …
This study was carried out to determine the transmitted genetic drug resistance profile in a …
Interaction between macrophage migration inhibitory factor and CD74 in human immunodeficiency virus type I infected primary monocyte-derived macrophages …
C Trifone, J Salido, MJ Ruiz, L Leng… - Frontiers in …, 2018 - frontiersin.org
Understanding the mechanisms of human immunodeficiency virus type I (HIV-1)
pathogenesis would facilitate the identification of new therapeutic targets to control the …
pathogenesis would facilitate the identification of new therapeutic targets to control the …
The mononuclear phagocyte system in infectious disease
G Lugo-Villarino, C Cougoule, E Meunier… - Frontiers in …, 2019 - frontiersin.org
The term “Mononuclear Phagocyte System”(MPS) was introduced by van Furth and Cohn in
1968 to describe a group of leukocytes that shared phenotypic features (eg, a single …
1968 to describe a group of leukocytes that shared phenotypic features (eg, a single …