Bacterial meningitis is a devastating infection, with a case fatality rate of up to 30% and 50%
of survivors developing neurological complications. These include short-term complications …

Objectives We reported on occurrence and impact of neurological sequelae after bacterial
meningitis. Methods We reviewed occurrence of neurological sequelae in children and …

Background Sepsis is one of the main reasons for non-elective admission to pediatric
intensive care units (PICUs), but little is known about determinants influencing outcome. We …

OBJECTIVE Central nervous system (CNS) infections cause significant morbidity and
mortality and often require neurosurgical intervention for proper diagnosis and treatment …

Objective: The objective of this study was to clarify the incidence and course of hearing loss
after bacterial meningitis to optimize the audiological follow-up. Data Sources: The …

Background: Bacterial meningitis is known to cause hearing impairments and neurologic
deficits; however, less is known regarding psychiatric disabilities. In this study, we assessed …

Introduction Acute bacterial meningitis (ABM) is a public health problem. The disease has
reemerged after the introduction of pneumococcal conjugate vaccines (PCVs) due to an …

Objective Pediatricians are well aware of the immediate risks of bacterial meningitis in
children. However, the long-term outcome of the disease has not been extensively studied …

Streptococcus species represent a significant global cause of meningitis, leading to brain
damage through bacterial virulence factors and the host inflammatory response. Upon …

A major Streptococcus pneumoniae pathogenic factor is the cholesterol-dependent cytolysin
pneumolysin, binding membrane cholesterol and producing permanent lytic or transient …