[HTML][HTML] Bridging the gap: investigating the link between Inflammasomes and postoperative cognitive dysfunction

S Zhang, C Liu, J Sun, Y Li, J Lu, X Xiong, L Hu… - Aging and …, 2023 - ncbi.nlm.nih.gov
Postoperative cognitive dysfunction (POCD) is a cluster of cognitive problems that may arise
after surgery. POCD symptoms include memory loss, focus inattention, and communication …

[HTML][HTML] LCP1 knockdown in monocyte-derived macrophages: mitigating ischemic brain injury and shaping immune cell signaling and metabolism

Y Wang, Q Yin, D Yang, H Jin, Y Yao, J Song, C Liu… - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: Ischemic stroke poses a significant health burden with limited treatment options.
Lymphocyte Cytosolic Protein 1 (LCP1) facilitates cell migration and immune responses by …

Nanomaterial-Based Strategies for Attenuating T-Cell-Mediated Immunodepression in Stroke Patients: Advancing Research Perspectives

Y Wang, C Liu, Y Ren, J Song, K Fan… - International Journal …, 2024 - Taylor & Francis
This review article discusses the potential of nanomaterials in targeted therapy and
immunomodulation for stroke-induced immunosuppression. Although nanomaterials have …

Serum bilirubin associated with stroke severity and prognosis: preliminary findings on liver function after acute ischemic stroke

H Duan, Z Cheng, HJ Yun, L Cai, Y Tong… - Neurological …, 2023 - Taylor & Francis
Objective This study investigates relationships between serum bilirubin, stroke severity, and
prognosis of patients with acute ischemic stroke (AIS) to elucidate the roles of the liver in …

[HTML][HTML] Dynamic detection of specific membrane capacitance and cytoplasmic resistance of neutrophils after ischemic stroke

H Zhao, X Luan, Y Wang, Y Ye, F Yan, X Li, Y Li… - Aging and …, 2023 - ncbi.nlm.nih.gov
Peripheral blood is the most readily available resource for stroke patient prognosis, but there
is a lack of methods to detect dynamic changes of neutrophils in peripheral blood that can …

Uncovering the dual roles of peripheral immune cells and their connections to brain cells in stroke and post-stroke stages through single-cell sequencing

Z Xu, F Yang, L Zheng - Frontiers in Neuroscience, 2024 - frontiersin.org
Ischemic stroke is a cerebrovascular disease that affects the blood vessels and the blood
supply to the brain, making it the second leading cause of death worldwide. Studies suggest …

Comprehensive immune modulation mechanisms of Angong Niuhuang Wan in ischemic stroke: Insights from mass cytometry analysis

Y Yao, W Ni, L Feng, J Meng, X Tan… - CNS Neuroscience …, 2024 - Wiley Online Library
Abstract Background Angong Niuhuang Wan (AGNHW, 安宫牛黄丸), is a classical medicinal
formula in Traditional Chinese Medicine (TCM) that has been appreciated for its …

A novel perspective in stroke neuroprotection: Leveraging hypoxic pocket insights for studying preconditioning and postconditioning

H Zhao, Y Meng, S Li, G Liu, X Ji - Neuroprotection, 2024 - Wiley Online Library
This perspective article delineates the significant role of hypoxic pockets—localized,
transient reductions in cerebral oxygenation—and their implications for stroke …