Fungal–fungal co-culture: a primer for generating chemical diversity

SL Knowles, HA Raja, CD Roberts… - Natural Product …, 2022 - pubs.rsc.org
Covering: 2002 to 2020 In their natural environment, fungi must compete for resources. It
has been hypothesized that this competition likely induces the biosynthesis of secondary …

Expanding the chemical diversity through microorganisms co-culture: Current status and outlook

D Arora, P Gupta, S Jaglan, C Roullier, O Grovel… - Biotechnology …, 2020 - Elsevier
Natural products (NPs) are considered as a cornerstone for the generation of bioactive leads
in drug discovery programs. However, one of the major limitations of NP drug discovery …

Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing

RV Kapoore, G Padmaperuma, S Maneein… - Critical Reviews in …, 2022 - Taylor & Francis
The application of microbial co-cultures is now recognized in the fields of biotechnology,
ecology, and medicine. Understanding the biological interactions that govern the …

Strategies to enhance production of metabolites in microbial co-culture systems

L Guo, B Xi, L Lu - Bioresource Technology, 2024 - Elsevier
Increasing evidence shows that microbial synthesis plays an important role in producing
high value-added products. However, microbial monoculture generally hampers metabolites …

Enhancing chemical and biological diversity by co-cultivation

DM Selegato, I Castro-Gamboa - Frontiers in microbiology, 2023 - frontiersin.org
In natural product research, microbial metabolites have tremendous potential to provide new
therapeutic agents since extremely diverse chemical structures can be found in the nearly …

Dynamics of metabolite induction in fungal co-cultures by metabolomics at both volatile and non-volatile levels

A Azzollini, L Boggia, J Boccard, B Sgorbini… - Frontiers in …, 2018 - frontiersin.org
Fungal co-cultivation has emerged as a promising way for activating cryptic biosynthetic
pathways and discovering novel antimicrobial metabolites. For the success of such studies …

Fungal social influencers: secondary metabolites as a platform for shaping the plant‐associated community

LI Rangel, O Hamilton, R de Jonge… - The Plant …, 2021 - Wiley Online Library
Fungal secondary metabolites (FSMs) are capable of manipulating plant community
dynamics by inhibiting or facilitating the establishment of co‐habitating organisms. Although …

Combination of Pseudo-LC-NMR and HRMS/MS-Based Molecular Networking for the Rapid Identification of Antimicrobial Metabolites From Fusarium petroliphilum

A Alfattani, L Marcourt, V Hofstetter… - Frontiers in Molecular …, 2021 - frontiersin.org
An endophytic fungal strain isolated from a seagrass endemic to the Mediterranean Sea
(Posidonia oceanica) was studied in order to identify its antimicrobial constituents and …

Genome-Wide Characterization Reveals Variation Potentially Involved in Pathogenicity and Mycotoxins Biosynthesis of Fusarium proliferatum Causing Spikelet Rot …

L Wang, S Ge, W Liang, W Liao, W Li, G Jiao, X Wei… - Toxins, 2022 - mdpi.com
Fusarium proliferatum is the primary cause of spikelet rot disease in rice (Oryza sativa L.) in
China. The pathogen not only infects a wide range of cereals, causing severe yield losses …

Metabolômica microbiana: inovações e aplicações

JR Belinato, JM Bazioli, A Sussulini, F Augusto… - Química nova, 2019 - SciELO Brasil
Over the past few years, metabolomics has been employed in a broad range of applications
in different research fields. Microbial metabolomics has been applied in several …