Glioblastoma: current status, emerging targets, and recent advances
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …
population of genetically unstable and highly infiltrative cells that are resistant to …
Neuropharmacological effect of risperidone: From chemistry to medicine
As the second-oldest atypical antipsychotic, risperidone has a long history of off-label usage
for treating behavioural and psychological signs and symptoms of dementia (BPSD), such …
for treating behavioural and psychological signs and symptoms of dementia (BPSD), such …
Intranasal delivery of Naloxone-loaded solid lipid nanoparticles as a promising simple and non-invasive approach for the management of opioid overdose
Naloxone is an opioid receptor antagonist that can eradicate all pre-indications of the toxicity
and inverse the opioid overdose. However, oral administration of naloxone offers limitations …
and inverse the opioid overdose. However, oral administration of naloxone offers limitations …
[HTML][HTML] Glioblastoma preclinical models: Strengths and weaknesses
Glioblastoma multiforme is a highly malignant brain tumor with significant intra-and
intertumoral heterogeneity known for its aggressive nature and poor prognosis. The complex …
intertumoral heterogeneity known for its aggressive nature and poor prognosis. The complex …
Lichen secondary metabolites inhibit the Wnt/β-catenin pathway in glioblastoma cells and improve the anticancer effects of Temozolomide
A Majchrzak-Celińska, R Kleszcz, E Studzińska-Sroka… - Cells, 2022 - mdpi.com
Lichens are a source of secondary metabolites with significant pharmacological potential.
Data regarding their possible application in glioblastoma (GBM) treatment are, however …
Data regarding their possible application in glioblastoma (GBM) treatment are, however …
Prognostic biomarker prediction for glioma induced by heavy metals and their mixtures: an in-silico study
HD Nguyen - Toxicology and Applied Pharmacology, 2023 - Elsevier
Although there is an association between heavy metals and glioma, the molecular
mechanisms involved in glioma development remain unclear. Therefore, this study aimed to …
mechanisms involved in glioma development remain unclear. Therefore, this study aimed to …
Role of scaffold proteins in the heterogeneity of glioblastoma
VJ Iyer, JE Donahue, MA Osman - Cell Communication and Signaling, 2024 - Springer
Glioblastoma (GB) is a highly heterogeneous type of incurable brain cancer with a low
survival rate. Intensive ongoing research has identified several potential targets; however …
survival rate. Intensive ongoing research has identified several potential targets; however …
A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration
Cardiomyocyte regeneration following cardiac damage is challenging to study because of
the inflammatory process, the multiplication of cells in the stroma, and the creation of scar …
the inflammatory process, the multiplication of cells in the stroma, and the creation of scar …
A multistep in silico approach identifies potential glioblastoma drug candidates via inclusive molecular targeting of glioblastoma stem cells
N Dogra, P Singh, A Kumar - Molecular Neurobiology, 2024 - Springer
Glioblastoma (GBM) is the highest grade of glioma for which no effective therapy is currently
available. Despite extensive research in diagnosis and therapy, there has been no …
available. Despite extensive research in diagnosis and therapy, there has been no …