The type III secretion machinery of Gram‐negative bacteria, also known as the injectisome
or needle complex, is composed of a basal body spanning both bacterial membranes and …

Many plant and animal bacterial pathogens assemble a needle-like nanomachine, the type
III secretion system (T3SS), to inject virulence proteins directly into eukaryotic cells to initiate …

Shigella spp. are food-and waterborne pathogens that cause severe diarrheal and
dysenteric disease associated with high morbidity and mortality. Individuals most often …

Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths
of millions worldwide, acting as key virulence elements in diseases ranging from plague to …

Varieties of Gram-negative bacterial pathogens infect their eukaryotic hosts by deploying the
type III translocon to deliver effector proteins into the cytosol of eukaryotic cells in which …

Type III secretion (TTS) is an essential virulence function for Shigella flexneri that delivers
effector proteins that are responsible for bacterial invasion of intestinal epithelial cells. The …

Many infectious Gram-negative bacteria, including Salmonella typhimurium, require a Type
Three Secretion System (T3SS) to translocate virulence factors into host cells. The T3SS …

Shigella flexneri uses its type III secretion apparatus (TTSA) to inject host-altering proteins
into targeted eukaryotic cells. The TTSA is composed of a basal body and an exposed …

Many plant‐and animal‐pathogenic G ram‐negative bacteria employ the type III secretion
system (T3SS) to translocate effector proteins from bacterial cells into the cytosol of …

Abstract Background Pathogenic Gram-negative bacteria interact with their eukaryotic hosts
by deploying the type III translocon to inject effector proteins into the cytosol of eukaryotic …