The human gastrointestinal tract contains the largest population of immune cells in the body
and this is a reflection of the fact that it is continuously exposed to a myriad of dietary and …

There is significant interest in understanding the cellular mechanisms responsible for
expedited healing response in various oral tissues and how they are impacted by systemic …

Impaired wound healing states lead to substantial morbidity and cost with treatment resulting
in an expenditure of billions of dollars per annum in the US alone. Both chronic wounds and …

Wounds in adults are frequently accompanied by scar formation. This scar can become
fibrotic due to an imbalance between extracellular matrix (ECM) synthesis and ECM …

On vascular damage, coagulation is initiated by extravascular tissue factor (TF).
Intravascular TF, which is present on circulating cell-derived vesicles, is noncoagulant under …

Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in
normal homoeostasis and at sites of inflammation. These include antiprotease and …

The immune system is continuously challenged with large quantities of exogenous antigens
at the barriers between the external environment and internal human tissues. Antimicrobial …

Sexually transmitted infections, and their associated sequelae, such as tubal infertility,
ectopic pregnancy and preterm labour, are a major worldwide health problem. Chlamydia …

Keratinocytes cover both the skin and some oral mucosa, but the morphology of each tissue
and the behavior of the keratinocytes from these two sites are different. One significant …

Wound healing is a complex biological process, comprised of a series of a sequential events
aiming to repair injured tissue. The role of the immune system in this process is not only to …