The maternal reward system in postpartum depression

C Post, B Leuner - Archives of women's mental health, 2019 - Springer
The experience of motherhood is most often emotionally positive and rewarding, but for
many new mothers suffering from postpartum depression (PPD), this is not the case …

The prolactin family of hormones as regulators of maternal mood and behavior

T Georgescu, JM Swart, DR Grattan… - Frontiers in Global …, 2021 - frontiersin.org
Transition into motherhood involves profound physiological and behavioral adaptations that
ensure the healthy development of offspring while maintaining maternal health. Dynamic …

Postpartum scarcity-adversity disrupts maternal behavior and induces a hypodopaminergic state in the rat dam and adult female offspring

M Rincón-Cortés, AA Grace - Neuropsychopharmacology, 2022 - nature.com
Postpartum adversity is among the strongest predictors for the emergence of postpartum
depression (PPD) in humans and a translational risk factor employed in rodent models …

Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases∆ FosB in D1 and D2 neurons in the nucleus …

WB Foster, KF Beach, PF Carson, KC Harris… - Hormones and …, 2023 - Elsevier
In placental mammals, estradiol levels are chronically elevated during pregnancy, but
quickly drop to prepartum levels following birth. This may produce an “estrogen withdrawal” …

Adaptations in reward-related behaviors and mesolimbic dopamine function during motherhood and the postpartum period

M Rincón-Cortés, AA Grace - Frontiers in neuroendocrinology, 2020 - Elsevier
Initiation and maintenance of maternal behavior is driven by a complex interaction between
the physiology of parturition and offspring stimulation, causing functional changes in …

[HTML][HTML] Bridging Neurobiological Insights and Clinical Biomarkers in Postpartum Depression: A Narrative Review

K Zhang, L He, Z Li, R Ding, X Han, B Chen… - International Journal of …, 2024 - mdpi.com
Postpartum depression (PPD) affects 174 million women worldwide and is characterized by
profound sadness, anxiety, irritability, and debilitating fatigue, which disrupt maternal …

Structural, functional, and metabolic signatures of postpartum depression: A systematic review

A Horáková, H Němcová, P Mohr, A Sebela - Frontiers in Psychiatry, 2022 - frontiersin.org
Objective Postpartum depression (PPD) is a serious condition with debilitating
consequences for the mother, offspring, and the whole family. The scope of negative …

Postpartum depression is associated with altered neural connectivity between affective and mentalizing regions during mother-infant interactions

JK Morgan, H Santosa, RM Fridley… - Frontiers in Global …, 2021 - frontiersin.org
Although there has been growing interest in mood-related neural alterations in women in the
initial weeks postpartum, recent work has demonstrated that postpartum depression often …

Preconception interpersonal personality features predict postpartum maternal parenting behaviors.

JB Northrup, B Llamas, EL Moses-Kolko… - Journal of Family …, 2023 - psycnet.apa.org
Individual differences in personality traits affect the quality of social relationships. The parent–
child relationship is among the most impactful social relationships in an individual's life, and …

Postpartum scarcity-adversity inflicts sex-specific cerebellar adaptations and reward behaviors in adolescence

M Maulik, K Looschen, C Smith, K Johnson… - Pharmacology …, 2023 - Elsevier
Early life adversity in the form of poor postnatal care is a major developmental stressor
impacting behavior later in life. Previous studies have shown the impact of early life stress …