From genome to epigenome: Who is a predominant player in the molecular hallmarks determining epigenetic mechanisms underlying ontogenesis?

M Samiec, M Trzcińska - Reproductive Biology, 2024 - Elsevier
Genetic factors are one of the basic determinants affecting ontogenesis in mammals.
Nevertheless, on the one hand, epigenetic factors have been found to exert the …

Downregulation of a potential therapeutic target NPAS2, regulated by p53, alleviates pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via …

Y Chen, Z He, B Zhao, R Zheng - Cellular Signalling, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease and a severe form of
pulmonary fibrosis. Epithelial-mesenchymal transition (EMT) of alveolar epithelial cells is …

[HTML][HTML] WNT10B: A locus increasing risk of brachygnathia inferior in Brown Swiss cattle

S Widmer, FR Seefried, IM Häfliger… - Journal of dairy …, 2023 - Elsevier
Shortening of the mandible (brachygnathia inferior) is a congenital, often inherited and
variably expressed craniofacial anomaly in domestic animals including cattle. Brachygnathia …

Genome-Wide Characterization of Somatic Mutation Patterns in Cloned Dogs Reveals Implications for Neuronal Function, Tumorigenesis, and Aging

SW Woo, M Kim, D Kang, Y Choe, SJ Oh, AS You… - Genes, 2024 - mdpi.com
Studies on somatic mutations in cloned animals have revealed slight genetic variances
between clones and their originals, but have yet to identify the precise effects of these …