Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Ghrelin is a stomach hormone that acts as an endogenous ligand of orphan G-protein-
coupled receptor. Ghrelin is a 28-amino acid peptide existing in two major forms: n-octanoyl …

Experimental studies have suggested that ghrelin plays a role in glucose homeostasis and
in the regulation of blood pressure (BP). We therefore assessed the hypothesis that a low …

Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Body composition exhibits marked variations across the early human lifetime. The precise
physiological mechanisms that drive such developmental adaptations are difficult to …

Summary objective Ghrelin, a novel endogenous ligand for the GH secretagogue receptor,
has been reported to have adipogenic actions and induce weight gain in addition to its GH …

Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …