Meconium, a non-invasive biomaterial reflecting prenatal substance accumulation, could
provide valuable insights into neonatal health. However, the comprehensive protein profile …

Centriolar satellites are ubiquitous membrane‐less organelles that play critical roles in
numerous cellular and organismal processes. They were initially discovered through …

Trisomy 21, the genetic cause of Down syndrome, disrupts primary cilia formation and
function, in part through elevated Pericentrin, a centrosome protein encoded on …

Various mammalian cells have autonomous cellular clocks that are produced by the
transcriptional cycle of clock genes. Cellular clocks provide circadian rhythms for cellular …

Trisomy 21 and mutations in the Sonic hedgehog (SHH) signaling pathway cause
overlapping and pleiotropic phenotypes including cerebellar hypoplasia, craniofacial …

Cellular processes require accurate and timely gene expression. An underexplored frontier
in post-transcriptional gene expression is the localization of RNA transcripts. Proper RNA …

Primary cilia are signaling organelles essential for development and homeostasis. Loss of
primary cilia is lethal, and decreased or defective cilia cause multisystemic conditions called …