Recent advances in extracellular vesicle engineering and its applications to regenerative medicine

WK Rhim, JY Kim, SY Lee, SG Cha, JM Park… - Biomaterials …, 2023 - spj.science.org
Extracellular vesicles (EVs) are nanosized particles that are released from cells and reflect
the characteristics of the mother cell. Recently, the EVs have been used in several types of …

Mesenchymal stem cell-derived exosomes: versatile nanomaterials for skin wound treatment

Y Xiao, H Li, J Zhang, S Yang, C Zhang, Y Huang… - Nano Research, 2024 - Springer
Accumulating studies reveal that mesenchymal stem cells (MSCs) promote skin wound
healing mainly through the paracrine effects. Exosomes, one of the crucial paracrine …

Emerging role of exosomes in cancer therapy: progress and challenges

J Li, J Wang, Z Chen - Molecular Cancer, 2025 - Springer
This review highlights recent progress in exosome-based drug delivery for cancer therapy,
covering exosome biogenesis, cargo selection mechanisms, and their application across …

Advanced 3D cell culture platform for tissue engineering

JK Yoon - Tissue Engineering and Regenerative Medicine, 2023 - Springer
In recent decades, the development and application of cell culture platforms has emerged as
a promising interdisciplinary field to address critical challenges in tissue engineering and …

[HTML][HTML] Spherical Shell Bioprinting to Produce Uniform Spheroids with Controlled Sizes

KH Son, DH Kim, S Park, HJ Kim, M Park… - Journal of Functional …, 2024 - mdpi.com
Conventional cell spheroid production methods are largely manual, leading to variations in
size and shape that compromise consistency and reliability for use in cell-based therapeutic …

[HTML][HTML] Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes

T Ohtsuki, I Sato, R Takashita… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a chronic disease affecting over 500 million people worldwide. As the
population ages and obesity rates rise, the societal burden of OA is increasing. Pro …

Extracellular Vesicles Derived From 3D Cultured Antler Stem Cells Serve as a New Drug Vehicle in Osteosarcoma Treatment

P Hu, J Ying, Y Wang, T Jiang, Z Pan… - Cell …, 2023 - journals.sagepub.com
Extracellular vesicles (EVs) from antler reserve mesenchymal (RM) cells play an important
role in the paracrine regulation during rapid growth of antler without forming a tumor; …

From bench to bedside: The promising value of exosomes in precision medicine for CNS tumors

M Wang, F Jin, X Tong - Heliyon, 2024 - cell.com
Exosomes are naturally present extracellular vesicles (EVs) released into the surrounding
body fluids upon the fusion of polycystic and plasma membranes. They facilitate intercellular …

[HTML][HTML] Spheroid-Exosome-Based Bioprinting Technology in Regenerative Medicine

HY Lee, JW Lee - Journal of Functional Biomaterials, 2024 - pmc.ncbi.nlm.nih.gov
Since the discovery that exosomes can exchange genes, their potential use as tools for
tissue regeneration, disease diagnosis, and therapeutic applications has drawn significant …

The Influence of Tacrolimus on Cellular Morphology, Cellular Viability, Osteogenic Differentiation, and mRNA Expression within Stem Cell Spheroids

WJ Park, SH Han, HJ Lee, JH Kim, HJ Song, JB Park - Medicina, 2024 - mdpi.com
Background and Objectives: Tacrolimus is a macrolide lactone compound derived from the
bacterium Streptomyces tsukubensis, widely known as an immunosuppressant. In basic …