Promise and pitfalls of heavy-particle therapy

T Mitin, AL Zietman - Journal of Clinical Oncology, 2014 - ascopubs.org
Proton beam therapy, the most common form of heavy-particle radiation therapy, is not a
new invention, but it has gained considerable public attention because of the high cost of …

Consensus statement on proton therapy in early-stage and locally advanced non–small cell lung cancer

JY Chang, SK Jabbour, D De Ruysscher… - International Journal of …, 2016 - Elsevier
Radiation dose escalation has been shown to improve local control and survival in patients
with non–small cell lung cancer in some studies, but randomized data have not supported …

The evolution of proton beam therapy: Current and future status

X Tian, K Liu, Y Hou, J Cheng… - … and clinical oncology, 2018 - spandidos-publications.com
Proton beam therapy (PBT) has been increasingly used in a variety of cancers due to its
excellent physical properties and superior dosimetric parameters. PBT may improve patient …

Acute toxicity in comprehensive head and neck radiation for nasopharynx and paranasal sinus cancers: cohort comparison of 3D conformal proton therapy and …

MW McDonald, Y Liu, MG Moore, PAS Johnstone - Radiation oncology, 2016 - Springer
Background To evaluate acute toxicity endpoints in a cohort of patients receiving head and
neck radiation with proton therapy or intensity modulated radiation therapy (IMRT). Methods …

[PDF][PDF] Towards high sensitivity and high-resolution PET scanners: imaging-guided proton therapy and total body imaging

K Lang - Bio-Algorithms and Med-Systems, 2022 - archive.sciendo.com
Quantitative imaging (ie, providing not just an image but also the related data) guidance in
proton radiation therapy to achieve and monitor the precision of planned radiation energy …

Radiosensitization effect of gold nanoparticles in proton therapy

C Cunningham, M de Kock, M Engelbrecht… - Frontiers in Public …, 2021 - frontiersin.org
The number of proton therapy facilities and the clinical usage of high energy proton beams
for cancer treatment has substantially increased over the last decade. This is mainly due to …

Flash irradiation with proton beams: beam characteristics and their implications for beam diagnostics

KP Nesteruk, S Psoroulas - applied sciences, 2021 - mdpi.com
FLASH irradiations use dose-rates orders of magnitude higher than commonly used in
patient treatments. Such irradiations have shown interesting normal tissue sparing in cell …

A review of dosimetric and toxicity modeling of proton versus photon craniospinal irradiation for pediatrics medulloblastoma

ESQ Ho, SA Barrett, LM Mullaney - Acta Oncologica, 2017 - Taylor & Francis
Background: Craniospinal irradiation (CSI) is the standard radiation therapy treatment for
medulloblastoma. Conventional CSI photon therapy (Photon-CSI) delivers significant dose …

Patterns of care in proton radiation therapy for pediatric central nervous system malignancies

B Odei, JE Frandsen, D Boothe, RP Ermoian… - International Journal of …, 2017 - Elsevier
Purpose Proton beam therapy (PBT) potentially allows for improved sparing of normal
tissues, hopefully leading to decreased late side effects in children. Using a national registry …

[HTML][HTML] Innovative radiotherapy of sarcoma: proton beam radiation

TF DeLaney, RLM Haas - European Journal of Cancer, 2016 - Elsevier
This review on proton beam radiotherapy (PBT) focusses on an historical overview, cost-
effectiveness, techniques, acute and late toxicities and clinical results of PBT for sarcoma …