Molecular Dynamics Simulations Predict that rSNP Located in the HNF-1α Gene Promotor Region Linked with MODY3 and Hepatocellular Carcinoma Promotes …

E Španinger, U Potočnik, U Bren - Biomolecules, 2020 - mdpi.com
Our study aims to investigate the impact of the Maturity-onset diabetes of the young 3
disease-linked rSNP rs35126805 located in the HNF-1α gene promotor on the binding of the …

An ensemble micro neural network approach for elucidating interactions between zinc finger proteins and their target DNA

S Dutta, S Madan, H Parikh, D Sundar - Bmc Genomics, 2016 - Springer
Background The ability to engineer zinc finger proteins binding to a DNA sequence of
choice is essential for targeted genome editing to be possible. Experimental techniques and …

Exploiting the recognition code for elucidating the mechanism of zinc finger protein-DNA interactions

S Dutta, S Madan, D Sundar - BMC genomics, 2016 - Springer
Background Engineering zinc finger protein motifs for specific binding to double-stranded
DNA is critical for targeted genome editing. Most existing tools for predicting DNA-binding …

[PDF][PDF] Développement d'outils moléculaires pour faciliter l'ingénierie des génomes

A Raymond Fleury - 2018 - core.ac.uk
Malgré les progrès récents associés à l'utilisation des nucléases d'ingénierie du génome,
certaines problématiques persistent. Par exemple, l'isolement des cellules génétiquement …

GIW and InCoB, two premier bioinformatics conferences in Asia with a combined 40 years of history

C Schönbach, P Horton, SM Yiu, TW Tan… - BMC genomics, 2015 - Springer
Abstract Knowledge discovery in bioinformatics thrives on joint and inclusive efforts of
stakeholders. Similarly, knowledge dissemination is expected to be more effective and …