Epithelial growth factor receptor (EGFR), a transmembrane receptor on the cell surface,
carries extracellular messages into the cell and alters the activity of the nucleus through …

Glycosylation, a key mode of protein modification in living organisms, is critical in regulating
various biological functions by influencing protein folding, transportation, and localization …

Gastric cancer is a remarkably heterogeneous tumor. Despite some advances in the
diagnosis and treatment of gastric cancer in recent years, the precise treatment and curative …

Abstract β-1, 4-GalT-V is an enzyme with glycosyltransferase activity that glycosylates
proteins and synthesizes the lactosylceramide sphingolipid in the Golgi apparatus …

Glycosylation is one of the most important post-translational modifications (PTMs) in a
protein, and is the most abundant and diverse biopolymer in nature. Glycans are involved in …

Colorectal cancer (CRC) develops mainly from colorectal advanced adenomas (AA), which
are considered precancerous lesions. Novel early diagnostic biomarkers are urgently …

Abstract β-1, 4-Galactosyltransferase-V (β-1, 4-GalT-V) is a membrane-bound glycoprotein
with glycosyltransferase enzyme activity that synthesizes lactosylceramide and glycosylates …

Protein glycosylation is a widespread posttranslational modification that can impact the
function of proteins. Dysregulated protein glycosylation has been linked to several diseases …

Purpose Colorectal cancer (CRC) has been reported as the second leading cause of cancer
death worldwide. The 5‐year annual survival is around 50%, mainly due to late diagnosis …

Colorectal cancer (CRC) ranks as the second most lethal cancer worldwide because of its
high rate of metastasis, and approximately 20% of CRC patients have metastases at initial …