Applications of network pharmacology in traditional Chinese medicine research

Z Zhou, B Chen, S Chen, M Lin, Y Chen… - Evidence‐Based …, 2020 - Wiley Online Library
Human diseases, especially infectious ones, have been evolving constantly. However, their
treatment strategies are not developing quickly. Some diseases are caused by a variety of …

Lycium ruthenicum studies: molecular biology, phytochemistry and pharmacology

H Wang, J Li, W Tao, X Zhang, X Gao, J Yong, J Zhao… - Food Chemistry, 2018 - Elsevier
Lycium ruthenicum has been used as ethnic medicine and nutraceutical food. Existing
studies of L. ruthenicum can be classifies into three areas:(1) those in which molecular …

Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis

G Yu, W Wang, X Wang, M Xu, L Zhang, L Ding… - … and alternative medicine, 2018 - Springer
Background Zuojinwan (ZJW), a classic herbal formula, has been extensively used to treat
gastric symptoms in clinical practice in China for centuries. However, the pharmacological …

Canine cognitive dysfunction: pathophysiology, diagnosis, and treatment

CW Dewey, ES Davies, H Xie… - … Clinics: Small Animal …, 2019 - vetsmall.theclinics.com
Canine cognitive dysfunction (CCD) is the canine analog of human Alzheimer disease (AD).
CCD is common in older dogs, particularly those more than 8 years old. Slowly progressive …

Classification-based strategies to simplify complex traditional Chinese medicine (TCM) researches through liquid chromatography-mass spectrometry in the last …

YH Chen, JH Bi, M Xie, H Zhang, ZQ Shi, H Guo… - … of Chromatography A, 2021 - Elsevier
The difficulty of traditional Chinese medicine (TCM) researches lies in the complexity of
components, metabolites, and bioactivities. For a long time, there has been a lack of …

Omics strategies decipher therapeutic discoveries of traditional Chinese medicine against different diseases at multiple layers molecular-level

R Guo, X Luo, J Liu, L Liu, X Wang, H Lu - Pharmacological research, 2020 - Elsevier
Traditional Chinese medicine (TCM) has been broadly used for the personalized treatment
of many diseases in China for thousands of years. In the past century, TCM was also …

Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease

F Maione, M Piccolo, S De Vita, MG Chini… - Pharmacological …, 2018 - Elsevier
Alzheimer's disease (AD) is a common form of dementia mainly characterized by the
deposition of neurofibrillary tangles and β-amyloid (Aβ) peptides in the brain. Additionally …

Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation

L Gao, K Wang, Y Zhou, J Fang, X Qin, G Du - Scientific reports, 2018 - nature.com
Abstract Compound Kushen Injection (CKI) is a Traditional Chinese Medicine (TCM)
preparation that has been clinically used in China to treat various types of solid tumours …

Traditional Ayurvedic and herbal remedies for Alzheimer's disease: from bench to bedside

R Sharma, K Kuca, E Nepovimova… - Expert review of …, 2019 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a progressive, neurodegenerative disorder
prevalent worldwide among elderly populations. Owing to limited efficacy, side effects, and …

Phytochemical Evaluation, Embryotoxicity, and Teratogenic Effects of Curcuma longa Extract on Zebrafish (Danio rerio)

AA Alafiatayo, KS Lai, A Syahida… - Evidence‐Based …, 2019 - Wiley Online Library
Curcuma longa L. is a rhizome plant often used as traditional medicinal preparations in
Southeast Asia. The dried powder is commonly known as cure‐all herbal medicine with a …