Functional hydrogels with tunable structures and properties for tissue engineering applications

X Li, Q Sun, Q Li, N Kawazoe, G Chen - Frontiers in chemistry, 2018 - frontiersin.org
Tissue engineering (TE) has been used as an attractive and efficient process to restore the
original tissue structures and functions through the combination of biodegradable scaffolds …

Glycosaminoglycans' ability to promote wound healing: from native living macromolecules to artificial Biomaterials

P Yang, Y Lu, W Gou, Y Qin, J Tan, G Luo… - Advanced …, 2024 - Wiley Online Library
Glycosaminoglycans (GAGs) are important for the occurrence of signaling molecules and
maintenance of microenvironment within the extracellular matrix (ECM) in living tissues …

Design of thiol-and light-sensitive degradable hydrogels using Michael-type addition reactions

PM Kharkar, KL Kiick, AM Kloxin - Polymer chemistry, 2015 - pubs.rsc.org
Injectable depots that respond to exogenous and endogenous stimuli present an attractive
strategy for tunable, patient-specific drug delivery. Here, the design of injectable and …

A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden poly (ethylene glycol) hydrogels

NE Friend, AJ McCoy, JP Stegemann, AJ Putnam - Biomaterials, 2023 - Elsevier
The formation of functional capillary blood vessels that can sustain the metabolic demands
of transplanted parenchymal cells remains one of the biggest challenges to the clinical …

Injectable Hydrogels in Cardiovascular Tissue Engineering

R Patel, D Patel - Polymers, 2024 - mdpi.com
Heart problems are quite prevalent worldwide. Cardiomyocytes and stem cells are two
examples of the cells and supporting matrix that are used in the integrated process of …

A bio-responsive, cargo-catchable gel for postsurgical tumor treatment via ICD-based immunotherapy

Q Chen, S Zhou, Y Ding, D Chen, NS Dahiru… - Journal of Controlled …, 2022 - Elsevier
Tumor recurrence and metastasis after surgery remain challenges for tumor treatment.
Strategy that can promote the immunogenicity, activate adaptative immune response and …

Cellular modulation by the elasticity of biomaterials

F Han, C Zhu, Q Guo, H Yang, B Li - Journal of Materials Chemistry B, 2016 - pubs.rsc.org
The behaviors and functions of individual cells, fundamental to the complexity of
multicellular organisms, are regulated by their integrated response to a variety of …

50th Anniversary Perspective: Polymeric Biomaterials: Diverse Functions Enabled by Advances in Macromolecular Chemistry

Y Liang, L Li, RA Scott, KL Kiick - Macromolecules, 2017 - ACS Publications
Biomaterials have been extensively used to leverage beneficial outcomes in various
therapeutic applications, such as providing spatial and temporal control over the release of …

[HTML][HTML] Protective effect of pterostilbene on sepsis-induced acute lung injury in a rat model via the JAK2/STAT3 pathway

H Xue, M Li - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
Background Bacterial infection is one of the most common causes of sepsis, with acute lung
injury (ALI) being a related complication. Pterostilbene (PTS) is extracted from blueberries …

Substrate stiffness directs the phenotype and polarization state of cord blood derived macrophages

RA Scott, KL Kiick, RE Akins - Acta biomaterialia, 2021 - Elsevier
Cord blood (CB) mononuclear cell populations have demonstrated significant promise in
biomaterials-based regenerative therapies; however, the contributions of monocyte and …