Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …

Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

The therapeutic efficacy of whole tumor cell vaccines (TCVs) is modest, which has delayed
their translation into personalized immunotherapies in the clinic. Here, we develop a TCV …

Cancer vaccine, which can promote tumor-specific immunostimulation, is one of the most
important immunotherapeutic strategies and holds tremendous potential for cancer …

Lung metastasis is challenging in patients with triple‐negative breast cancer (TNBC).
Surgery is always not available due to the dissemination of metastatic foci and most drugs …

Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

Although CRISPR-mediated genome editing holds promise for cancer therapy, inadequate
tumor targeting and potential off-target side effects hamper its outcomes. In this study, we …

Toll-like receptor (TLR) agonists are potent immune-stimulators that hold great potential in
vaccine adjuvants as well as cancer immunotherapy. However, TLR agonists in free form …

Despite the superior tumor lytic efficacy of oncolytic viruses (OVs), their systemic delivery still
faces the challenges of limited circulating periods, poor tumor tropism, and spontaneous …

The development of bacterial vaccines for inducing an immunoresponse against infectious
diseases such as osteomyelitis is of great significance and importance. However, the …