[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

The role of oxidative stress in the aging heart

LU Pagan, MJ Gomes, M Gatto, GAF Mota, K Okoshi… - Antioxidants, 2022 - mdpi.com
Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Reactive oxygen species as intracellular signaling molecules in the cardiovascular system

AV Krylatov, LN Maslov, NS Voronkov… - Current cardiology …, 2018 - ingentaconnect.com
Background: Redox signaling plays an important role in the lives of cells. This signaling not
only becomes apparent in pathologies but is also thought to be involved in maintaining …

Exercise-induced regulation of redox status in cardiovascular diseases: the role of exercise training and detraining

T Tofas, D Draganidis, CK Deli, K Georgakouli… - Antioxidants, 2019 - mdpi.com
Although low levels of reactive oxygen species (ROS) are beneficial for the organism
ensuring normal cell and vascular function, the overproduction of ROS and increased …

[HTML][HTML] Cardiac cachexia: perspectives for prevention and treatment

MP Okoshi, RV Capalbo, FG Romeiro… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its
occurrence predicts increased morbidity and mortality independent of important clinical …

Effects of aerobic and resistance exercise on cardiac remodelling and skeletal muscle oxidative stress of infarcted rats

MJ Gomes, LU Pagan, ARR Lima… - Journal of cellular …, 2020 - Wiley Online Library
We compared the influence of aerobic and resistance exercise on cardiac remodelling,
physical capacity and skeletal muscle oxidative stress in rats with MI‐induced heart failure …

Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus

R Gimenes, C Gimenes, CM Rosa, NP Xavier… - Cardiovascular …, 2018 - Springer
Background Increased reactive oxygen species (ROS) generation in diabetes mellitus (DM)
is an important mechanism leading to diabetic cardiomyopathy. Apocynin, a drug isolated …

[HTML][HTML] Modulation of MAPK and NF-κB signaling pathways by antioxidant therapy in skeletal muscle of heart failure rats

PF Martinez, C Bonomo, DM Guizoni… - Cellular physiology and …, 2016 - karger.com
Background/Aims: Although increased oxidative stress plays a role in heart failure (HF)-
induced skeletal myopathy, signaling pathways involved in muscle changes and the role of …

Physical exercise is a potential “medicine” for atherosclerosis

J Yang, RY Cao, R Gao, Q Mi, Q Dai, F Zhu - Exercise for Cardiovascular …, 2017 - Springer
Cardiovascular disease (CVD) has been recognized as the number one killer for decades.
The most well-known risk factor is atherosclerosis. Unlike the acuity of CVD, atherosclerosis …

Effects of Long‐Term Regular Continuous and Intermittent Walking on Oxidative Stress, Metabolic Profile, Heart Rate Variability, and Blood Pressure in Older Adults …

P Prasertsri, J Phoemsapthawee… - … and Public Health, 2022 - Wiley Online Library
It is documented that regular exercise is beneficial for improving the antioxidant system,
metabolic system, cardiac autonomic function, and blood pressure in those with …