Cancer is a type of malignant affliction threatening human health worldwide; however, the
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …

LncRNAs function as molecular sponges for miRNAs to control their availability for targeting
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …

Doublecortin-like kinase 1 (DCLK1), a protein molecule, has been identified as a tumor stem
cell marker in the cancer cells of gastrointestinal, pancreas, and human colon. DCLK1 …

Casein kinase 1ε (CK1ε) and axis inhibitor 1 (AXIN1) are crucial components of the β‐
catenin destruction complex in canonical Wnt signaling. CK1ε has been shown to interact …

Tuft cells are more than guardian chemosensory elements of the digestive tract. They
produce a variety of immunological effector molecules in response to stimulation; moreover …

Most colorectal cancers (CRC) are associated with activated Wnt signaling, making it the
fourth most prevalent type of cancer globally. To function properly, the Wnt signaling …

Background Pelvic malignancies consistently pose significant global health challenges,
adversely affecting the well-being of the male population. It is anticipated that clinicians will …

Objective: The aim of this project is to identify the differences in expression levels of stem
cell related genes (SCRGs) in normal colon tissue, histopathologically staged colon polyps …