Recent developments of C-4 substituted coumarin derivatives as anticancer agents

J Dandriyal, R Singla, M Kumar, V Jaitak - European journal of medicinal …, 2016 - Elsevier
Cancer is a prominent cause of death in global. Currently, the numbers of drugs that are in
clinical practice are having a high prevalence of side effect and multidrug resistance …

Green chemistry approaches to the synthesis of coumarin derivatives

M Molnar, M Lončarić, M Kovač - Current organic chemistry, 2020 - ingentaconnect.com
This review is a compilation of the green synthetic methods used in the synthesis of
coumarin derivatives. Coumarins are a class of compounds with a pronounced wide range …

Past, present and future of the Biginelli reaction: a critical perspective.

JS Sandhu - ARKIVOC: Online Journal of Organic …, 2012 - search.ebscohost.com
This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

Pechmann reaction in the synthesis of coumarin derivatives

MM Heravi, S Khaghaninejad, M Mostofi - Advances in heterocyclic …, 2014 - Elsevier
The Pechmann reaction introduces one of the most significant and simple methods for the
synthesis of a variety of heterocyclic compounds, particularly coumarin derivatives. In 1883 …

The three‐component Biginelli reaction: a combined experimental and theoretical mechanistic investigation

ROMA De Souza, ET da Penha… - … A European Journal, 2009 - Wiley Online Library
Biginelli reactions have been monitored by direct infusion electrospray ionization mass
spectrometry (ESI‐MS) and key cationic intermediates involved in this three‐component …

Biginelli reaction: a green perspective

S S. Panda, P Khanna, L Khanna - Current Organic Chemistry, 2012 - benthamdirect.com
The Biginelli Reaction is a one-pot acid catalysed cyclocondensation of β-keto ester, urea
and aromatic aldehyde which leads to the synthesis of functionalised 3, 4-dihydro-2 (H) …

Simple coumarins: privileged scaffolds in medicinal chemistry

MFM Borges, FMF Roleira… - … Chemistry: Volume 4, 2009 - benthamdirect.com
Coumarins, also known as benzopyrones, are present in remarkable amounts in plants,
although their presence has also been detected in microorganisms and animal sources. The …

New potential of the classical Biginelli reaction

SV Vdovina, VA Mamedov - Russian Chemical Reviews, 2008 - iopscience.iop.org
The published data on the Biginelli reaction are generalised and systematised. The major
attention is focused on the publications of the last seven years. Possible reaction …

TaBr5-catalyzed Biginelli reaction: one-pot synthesis of 3, 4-dihydropyrimidin-2-(1H)-ones/thiones under solvent-free conditions

N Ahmed, JE van Lier - Tetrahedron letters, 2007 - Elsevier
An efficient TaBr5 (5–10mol%)-catalyzed Biginelli reaction under solvent-free conditions for
one-pot syntheses of 3, 4-dihydropyrimidin-2-(1H)-ones (DHPMs) and their thione analogs …

One-pot green procedure for Biginelli reaction catalyzed by novel task-specific room-temperature ionic liquids

F Dong, L Jun, Z Xinli, Y Zhiwen, L Zuliang - Journal of Molecular Catalysis …, 2007 - Elsevier
Cheap and reusable task-specific ionic liquids that bear an alkanesulfonic acid group in an
acyclic trialkylammonium cation were found to be effective catalysts for synthesizing 3, 4 …