Coagulation disorders in sepsis and COVID-19—two sides of the same coin? A review of inflammation–coagulation crosstalk in bacterial sepsis and COVID-19

G Tuculeanu, EC Barbu, M Lazar… - Journal of Clinical …, 2023 - mdpi.com
Sepsis is a major cause of morbidity and mortality worldwide. Sepsis-associated coagulation
disorders are involved in the pathogenesis of multiorgan failure and lead to a subsequently …

The influence of environmental hypoxia on hemostasis—A systematic review

B Treml, B Wallner, C Blank, D Fries… - Frontiers in …, 2022 - frontiersin.org
Humans have been ascending to high altitudes for centuries, with a growing number of
professional-and leisure-related sojourns occurring in this millennium. A multitude of …

The human platelet transcriptome and proteome is altered and pro-thrombotic functional responses are increased during prolonged hypoxia exposure at high altitude

C Shang, T Wuren, Q Ga, Z Bai, L Guo, AS Eustes… - Platelets, 2020 - Taylor & Francis
Exposure to hypoxia, through ascension to high altitudes (HAs), air travel, or human
disease, is associated with an increased incidence of thrombosis in some settings …

Chymase inhibition resolves and prevents deep vein thrombosis without increasing bleeding time in the mouse model

C Lapointe, L Vincent, H Giguère… - Journal of the …, 2023 - Am Heart Assoc
Background Deep vein thrombosis (DVT) is the primary cause of pulmonary embolism and
the third most life‐threatening cardiovascular disease in North America. Post‐DVT …

Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia

Z Wang, N Tenzing, Q Xu, H Liu, Y Ye, Y Wen, T Wuren… - Platelets, 2023 - Taylor & Francis
High-altitude polycythemia (HAPC) can occur in individuals who are intolerant to high-
altitude hypoxia. In patients with HAPC, erythrocytosis is often accompanied by a decrease …

Exercise and hypoxia-induced hypercoagulability is counterbalanced in women in part by decreased platelet reactivity

M Ninivaggi, F Swieringa, H Middelveld… - Thrombosis …, 2024 - Elsevier
Hypoxia plays an important role in several pathologies, eg chronic obstructive pulmonary
disease and obstructive sleep apnea syndrome, and is linked to an increased thrombosis …

Central venous catheter-related deep vein thrombosis in the pediatric cardiac intensive care unit

EH Steen, JJ Lasa, TC Nguyen, SG Keswani… - Journal of Surgical …, 2019 - Elsevier
Background Central venous catheter (CVC) use is common in the management of critically
ill children, especially those with congenital heart disease. CVCs are known to augment the …

Effects of repeated bouts of exercise on the hemostatic system

LN van der Vorm, D Huskens… - … in thrombosis and …, 2018 - thieme-connect.com
Physical activity is beneficial for health, for example, by lowering the risk of cardiovascular
events. However, vigorous exercise is associated with the occurrence of thromboembolic …

JAK2 mutation assessment in thrombotic events at unusual anatomical sites: insights from a high-altitude cohort

HY Alkhaldy, AO Yahya, AM Algarni… - … Journal of General …, 2024 - Taylor & Francis
Introduction Thrombosis stands as a significant contributor to both morbidity and mortality in
individuals afflicted with myeloproliferative neoplasms. This retrospective study investigated …

Emerging patterns of hypercoagulability associated with critical COVID-19: A review

JS Frazer, AJT Everden - Trends in Anaesthesia and Critical Care, 2020 - Elsevier
While the COVID-19 pandemic sweeps the world, much evidence is being gathered
regarding its novel pathological mechanisms. It is the authors' clinical experience that …