The Covid-19 pandemic has introduced an array of organspecific and systemic phenotypes-
some previously observed in viral infections, including severe acute respiratory syndrome …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

In recent years, the traditional view of the hemostatic system as being regulated by a
coagulation factor cascade coupled with platelet activation has been increasingly …

Histones and their post-translational modifications have key roles in chromatin remodeling
and gene transcription. Besides intranuclear functions, histones act as damage-associated …

Essentials• Neutrophil extracellular traps (NETs) might play a role in cancer‐related
coagulopathy.• We determined NET biomarkers and followed cancer patients for venous …

Well established for their central role in hemostasis, platelets have increasingly been
appreciated as immune cells in recent years. This emerging role should not come as a …

Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …

Neutrophil NETosis is an important element of host defense as it catapults chromatin out of
the cell to trap bacteria, which then are killed, eg, by the chromatin's histone component …

Venous thrombosis (VT), a leading cause of morbidity and mortality worldwide, has recently
been linked to neutrophil activation and release of neutrophil extracellular traps (NETs) via a …

Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …