Forest and trees: exploring bacterial virulence with genome-wide association studies and machine learning

JP Allen, E Snitkin, NB Pincus, AR Hauser - Trends in microbiology, 2021 - cell.com
The advent of inexpensive and rapid sequencing technologies has allowed bacterial whole-
genome sequences to be generated at an unprecedented pace. This wealth of information …

Using omics technologies and systems biology to identify epitope targets for the development of monoclonal antibodies against antibiotic-resistant bacteria

AJ Martín-Galiano, MJ McConnell - Frontiers in Immunology, 2019 - frontiersin.org
Over the past few decades, antimicrobial resistance has emerged as an important threat to
public health due to the global dissemination of multidrug-resistant strains from several …

Molecular docking and proteomics reveals the synergistic antibacterial mechanism of theaflavin with β-lactam antibiotics against MRSA

S Guan, L Zhong, H Yu, L Wang, Y Jin, J Liu… - Frontiers in …, 2022 - frontiersin.org
Recurrent epidemics of methicillin-resistant Staphylococcus aureus (S. aureus)(MRSA) have
illustrated that the effectiveness of antibiotics in clinical application is rapidly fading. A …

Leveraging big data bioinformatics approaches to extract knowledge from Staphylococcus aureus public omics data

D Subramanian, J Natarajan - Critical Reviews in Microbiology, 2023 - Taylor & Francis
Staphylococcus aureus is a notorious pathogen posing challenges in the medical industry
due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus …

BiomeNet: a database for construction and analysis of functional interaction networks for any species with a sequenced genome

E Kim, D Bae, S Yang, G Ko, S Lee, B Lee, I Lee - Bioinformatics, 2020 - academic.oup.com
Motivation Owing to advanced DNA sequencing and genome assembly technology, the
number of species with sequenced genomes is rapidly increasing. The aim of the recently …

[PDF][PDF] Comparative genomics and transcriptomics elucidate virulence mechanisms and host responses in infectious diseases

T Sae-Ong - 2022 - db-thueringen.de
COMPARATIVE GENOMICS AND TRANSCRIPTOMICS ELUCIDATE VIRULENCE MECHANISMS
AND HOST RESPONSES IN INFECTIOUS DISEASES by M.Sc. Tongt Page 1 COMPARATIVE …

Analysis of Antimicrobial resistance gene in Staphylococcus aureus by Gene Networking using Cytoscape

ME Santhosh, PK Selvam, K Vasudevan - 2023 - researchsquare.com
Antibiotic resistance One of the major global issues of this century is AMR among
microorganisms, which is still a challenge for mankind. It's crucial to understand the genes …

[引用][C] Systems vaccinology for identification of new antigen (s) for designing a broad-spectrum epitope-based vaccine against Staphylococcus aureus

A Salemi - 2020 - Tabriz University of Medical …