The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …

Circular dichroism (CD) spectroscopy is a widely used method to study the protein
secondary structure. However, for decades, the general opinion was that the correct …

Systemic lupus erythematosus (SLE) patients exhibit accelerated development of
atherosclerosis and increased incidents of cardiovascular disease (CVD) that cannot be …

Amyloid fibrils are insoluble, fibrous nanostructures that accumulate extracellularly in
biological tissue during the progression of several human disorders, including Alzheimer's …

Patients with plasma cell dyscrasias produce free abnormal monoclonal immunoglobulin
light chains that circulate in the blood stream. Some of them, termed glomerulopathic light …

Apolipoprotein AI (ApoA-I) amyloidosis is a rare protein misfolding disease where fibrils of
the N-terminal domain of the protein accumulate in several organs, leading to their failure …

Abstract Apolipoprotein AI (apoA-I) shares with other exchangeable apolipoproteins a high
level of structural plasticity. In the lipid-free state, the apolipoprotein amphipathic α-helices …

The review highlights various aspects of the influence of chaperones on amyloid proteins
associated with the development of neurodegenerative diseases and includes studies …

Amyloid deposits of WT apolipoprotein AI (apoA-I), the main protein component of high-
density lipoprotein, accumulate in atherosclerotic plaques where they may contribute to …