In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

Cognitive impairment is one of the most important negative consequences associated with
cannabis consumption. We found that CB1 cannabinoid receptor (CB1R) activation …

Autism spectrum disorders (ASDs) are four times more common in males than in females,
but the underlying mechanisms are poorly understood. We characterized sexually dimorphic …

MDGA (MAM domain containing glycosylphosphatidylinositol anchor) family proteins were
previously identified as synaptic suppressive factors. However, various genetic …

Social deficits are observed in diverse psychiatric disorders, including autism spectrum
disorders and schizophrenia. We found that mice lacking the excitatory synaptic signaling …

Dynamic plasma membrane rearrangements occur during many cellular processes
including endocytosis, morphogenesis, and migration. Actin polymerization together with …

Actin polymerization governs activity-dependent modulation of excitatory synapses,
including their morphology and functionality. It is clear from human genetics that …

Mounting evidence in animal models indicates potential for rejuvenation of cellular and
cognitive functions in the aging brain. However, the ability to utilize this potential is …

ADNP syndrome, involving the ADNP transcription factor of the SWI/SNF chromatin-
remodeling complex, is characterized by developmental delay, intellectual disability, and …