Ovarian cancer is known as a serious malignancy that affects women's reproductive tract and can considerably threat their health. A wide range of molecular mechanisms and …
Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …
J Kim, EY Park, O Kim, JM Schilder, DM Coffey… - Cancers, 2018 - mdpi.com
High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …
KM Nieman, HA Kenny, CV Penicka, A Ladanyi… - Nature medicine, 2011 - nature.com
Intra-abdominal tumors, such as ovarian cancer,, have a clear predilection for metastasis to the omentum, an organ primarily composed of adipocytes. Currently, it is unclear why tumor …
C Marchetti, F De Felice, A Romito, V Iacobelli… - Seminars in Cancer …, 2021 - Elsevier
Ovarian cancer (OC) remains a fatal malignancy because most patients experience recurrent disease, which is resistant to chemotherapy. The outcomes for patients with …
BG Bitler, KM Aird, A Garipov, H Li, M Amatangelo… - Nature medicine, 2015 - nature.com
The gene encoding ARID1A, a chromatin remodeler, shows one of the highest mutation rates across many cancer types. Notably, ARID1A is mutated in over 50% of ovarian clear …
Recent morphologic, immunohistochemical, and molecular genetic studies have led to the development of a new paradigm for the pathogenesis and origin of epithelial ovarian cancer …
The purpose of this review is to present the current state of the role of imaging in photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …
RJ Kurman, IM Shih - The American journal of surgical pathology, 2010 - journals.lww.com
Ovarian cancer is the most lethal gynecologic malignancy. Efforts at early detection and new therapeutic approaches to reduce mortality have been largely unsuccessful, because the …