Mechanosensing by Piezo1 and its implications for physiology and various pathologies

A Lai, CD Cox, N Chandra Sekar… - Biological …, 2022 - Wiley Online Library
Piezo1 is a mechanosensitive ion channel with essential roles in cardiovascular, lung,
urinary, and immune functions. Piezo1 is widely distributed in different tissues in the human …

Cardiovascular and neurological causes of sudden death after ischaemic stroke

P Sörös, V Hachinski - The Lancet Neurology, 2012 - thelancet.com
Sudden death is an important but widely under-recognised consequence of stroke. Acute
stroke can disturb central autonomic control, resulting in myocardial injury …

Point: Counterpoint: Cardiovascular variability is/is not an index of autonomic control of circulation

G Parati, G Mancia, MD Rienzo… - Journal of applied …, 2006 - journals.physiology.org
PURPOSE AND SCOPE OF THE POINT: COUNTERPOINT DEBATES This series of
debates was initiated for the Journal of Applied Physiology because we believe an important …

The immune system and hypertension

MV Singh, MW Chapleau, SC Harwani… - Immunologic …, 2014 - Springer
A powerful interaction between the autonomic and the immune systems plays a prominent
role in the initiation and maintenance of hypertension and significantly contributes to …

Cerebrogenic cardiac arrhythmias: cortical lateralization and clinical significance

S Oppenheimer - Clinical Autonomic Research, 2006 - Springer
That the brain may be involved in cardiovascular regulation has been acknowledged for
over a century. That cardiac arrhythmias may result from cortical derangement has been less …

Heart rate variability as a biomarker for predicting stroke, post-stroke complications and functionality

T Lees, F Shad-Kaneez, AM Simpson… - Biomarker …, 2018 - journals.sagepub.com
Background: Heart rate variability (HRV) is a non-invasive measure of the function of the
autonomic nervous system, and its dynamic nature may provide a means through which …

The insular cortex and the regulation of cardiac function

S Oppenheimer, D Cechetto - Comprehensive Physiology, 2011 - Wiley Online Library
Cortical representation of the heart challenges the orthodox view that cardiac regulation is
confined to stereotyped, preprogrammed and rigid responses to exteroceptive or …

Integrative cerebral blood flow regulation in ischemic stroke

JL Fan, P Brassard, CA Rickards… - Journal of Cerebral …, 2022 - journals.sagepub.com
Optimizing cerebral perfusion is key to rescuing salvageable ischemic brain tissue. Despite
being an important determinant of cerebral perfusion, there are no effective guidelines for …

[HTML][HTML] The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation

Y Lu, X Ma, R Sabharwal, V Snitsarev, D Morgan… - Neuron, 2009 - cell.com
Arterial baroreceptors provide a neural sensory input that reflexly regulates the autonomic
drive of circulation. Our goal was to test the hypothesis that a member of the acid-sensing …

Prognostic implications of right-sided insular damage, cardiac autonomic derangement, and arrhythmias after acute ischemic stroke

F Colivicchi, A Bassi, M Santini, C Caltagirone - Stroke, 2005 - Am Heart Assoc
Background and Purpose—Acute stroke is associated with impairment of cardiac autonomic
balance and increased incidence of arrhythmias. These abnormalities appear more relevant …