[HTML][HTML] Extracellular matrix signals as drivers of mitochondrial bioenergetics and metabolic plasticity of cancer cells during metastasis
FA Urra, S Fuentes-Retamal, C Palominos… - Frontiers in cell and …, 2021 - frontiersin.org
The role of metabolism in tumor growth and chemoresistance has received considerable
attention, however, the contribution of mitochondrial bioenergetics in migration, invasion …
attention, however, the contribution of mitochondrial bioenergetics in migration, invasion …
Pharmacological updates of nifuroxazide: promising preclinical effects and the underlying molecular mechanisms
Nifuroxazide (NFX) is a safe nitrofuran antibacterial drug used clinically to treat acute
diarrhea and infectious traveler diarrhea or colitis. Recent studies revealed that NFX …
diarrhea and infectious traveler diarrhea or colitis. Recent studies revealed that NFX …
[HTML][HTML] Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling
S Saber, EE Abd El-Fattah, AM Abdelhamid… - Biomedicine & …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
[HTML][HTML] RAC3 promotes proliferation, migration and invasion via PYCR1/JAK/STAT signaling in bladder cancer
C Cheng, D Song, Y Wu, B Liu - Frontiers in molecular biosciences, 2020 - frontiersin.org
Background Bladder cancer (BCa) represents one of the most common malignant cancers
with high incidence and mortality rates globally. Dysregulation of gene expression has been …
with high incidence and mortality rates globally. Dysregulation of gene expression has been …
Toward a repositioning of the antibacterial drug nifuroxazide for cancer treatment
C Bailly - Drug Discovery Today, 2019 - Elsevier
Highlights•The antibacterial drug nifuroxazide has been used to treat infectious diarrhoea
since 1966.•Potent inhibition of STAT3 by NFX confers antitumour and inflammatory …
since 1966.•Potent inhibition of STAT3 by NFX confers antitumour and inflammatory …
A novel role of nifuroxazide in attenuation of sepsis-associated acute lung and myocardial injuries; role of TLR4/NLPR3/IL-1β signaling interruption
Acute lung injury (ALI) and the subsequent multi-system organ failure is a serious health
problem with devastating impacts on the health care systems. Indeed, the world has been …
problem with devastating impacts on the health care systems. Indeed, the world has been …
[HTML][HTML] Nifuroxazide mitigates angiogenesis in ehlrich's solid carcinoma: molecular docking, bioinformatic and experimental studies on inhibition of il-6/jak2/stat3 …
Nifuroxazide is an antidiarrheal medication that has promising anticancer activity against
diverse types of tumors. The present study tested the anticancer activity of nifuroxazide …
diverse types of tumors. The present study tested the anticancer activity of nifuroxazide …
Drug repurposing: An emerging strategy in alleviating skin cancer
P Kumbhar, K Kole, T Yadav, A Bhavar… - European Journal of …, 2022 - Elsevier
Skin cancer is one of the most common forms of cancer. Several million people are
estimated to have affected with this condition worldwide. Skin cancer generally includes …
estimated to have affected with this condition worldwide. Skin cancer generally includes …
Simultaneous determination of eight nitrofuran residues in shellfish and fish using ultra-high performance liquid chromatography–tandem mass spectrometry
G Yuan, Z Zhu, P Yang, S Lu, H Liu, W Liu… - Journal of Food …, 2020 - Elsevier
Illegal use of nitrofurans (NFs) in aquaculture is of great concern for food safety throughout
the world. A liquid chromatography-based method coupled to tandem mass spectrometry …
the world. A liquid chromatography-based method coupled to tandem mass spectrometry …
[HTML][HTML] Nifuroxazide induces the apoptosis of human non‑small cell lung cancer cells through the endoplasmic reticulum stress PERK signaling pathway
D Li, L Liu, F Li, C Ma, K Ge - Oncology Letters, 2023 - spandidos-publications.com
The aim of the present study was to investigate the molecular mechanism of nifuroxazide
(NFZ) in the induction of apoptosis of NCI‑H1299 human non‑small cell lung cancer …
(NFZ) in the induction of apoptosis of NCI‑H1299 human non‑small cell lung cancer …