Psychological stress and cellular aging in cancer: A meta‐analysis

J Kruk, BH Aboul-Enein, J Bernstein… - … medicine and cellular …, 2019 - Wiley Online Library
Background. Epidemiological evidence continues to accumulate on the effect of
psychosocial and behavioral factors in relation to cancer risk, progression, and mortality …

Causes and mechanisms of hematopoietic stem cell aging

J Lee, SR Yoon, I Choi, H Jung - International Journal of Molecular …, 2019 - mdpi.com
Many elderly people suffer from hematological diseases known to be highly age-dependent.
Hematopoietic stem cells (HSCs) maintain the immune system by producing all blood cells …

Oxidative stress and dementia in Alzheimer's patients: effects of synbiotic supplementation

AMM Ton, BP Campagnaro, GA Alves… - Oxidative medicine …, 2020 - Wiley Online Library
Background. Alzheimer's disease (AD) is the most common cause of dementia in elderly
patients. Recently, several studies have shown that inflammation and oxidative stress …

Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets

TY Su, J Hauenstein, E Somuncular, Ö Dumral… - Nature …, 2024 - nature.com
Age is a risk factor for hematologic malignancies. Attributes of the aging hematopoietic
system include increased myelopoiesis, impaired adaptive immunity, and a functional …

[HTML][HTML] Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss

MA Olesen, AK Torres, C Jara, MP Murphy… - Redox biology, 2020 - Elsevier
Aging is a process characterized by cognitive impairment and mitochondrial dysfunction. In
neurons, these organelles are classified as synaptic and non-synaptic mitochondria …

Energy metabolism plays a critical role in stem cell maintenance and differentiation

C Hu, L Fan, P Cen, E Chen, Z Jiang, L Li - International journal of …, 2016 - mdpi.com
Various stem cells gradually turned to be critical players in tissue engineering and
regenerative medicine therapies. Current evidence has demonstrated that in addition to …

Metabolic syndrome as a multifaceted risk factor for oxidative stress

S Spahis, JM Borys, E Levy - Antioxidants & redox signaling, 2017 - liebertpub.com
Abstract Significance: Metabolic syndrome (MetS) is associated with a greater risk of
diabetes and cardiovascular diseases. It is estimated that this multifactorial condition affects …

Carcinogenesis and reactive oxygen species signaling: Interaction of the NADPH oxidase NOX1–5 and superoxide dismutase 1–3 signal transduction pathways

A Parascandolo, MO Laukkanen - Antioxidants & redox signaling, 2019 - liebertpub.com
Abstract Significance: Reduction/oxidation (redox) balance could be defined as an even
distribution of reduction and oxidation complementary processes and their reaction end …

Mitophagy plays a central role in mitochondrial ageing

A Diot, K Morten, J Poulton - Mammalian Genome, 2016 - Springer
The mechanisms underlying ageing have been discussed for decades, and advances in
molecular and cell biology of the last three decades have accelerated research in this area …

A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease

V Olivari, SM Di Modica, MR Lidonnici, M Aghajan… - Kidney International, 2023 - Elsevier
Anemia is a common complication of systemic inflammation. Proinflammatory cytokines both
decrease erythroblast sensitivity to erythropoietin (EPO) and increase the levels of the …