Background A significant proportion of patients with Tourette syndrome (TS) continue to
experience symptoms across adulthood that in severe cases fail to respond to standard …

Deep brain stimulation (DBS) may improve disabling tics in severely affected medication
and behaviorally resistant Tourette syndrome (TS). Here we review all reported cases of TS …

Abstract In 2011 the European Society for the Study of Tourette Syndrome (ESSTS)
published its first European clinical guidelines for the treatment of Tourette Syndrome (TS) …

Because of our limited knowledge of the functional role of the thalamostriatal system, this
massive network is often ignored in models of the pathophysiology of brain disorders of …

Deep brain stimulation of the thalamus has been proposed as a therapeutic option in
patients with Tourette syndrome who are refractory to pharmacological and …

Invasive and noninvasive neurostimulation therapies for obsessive-compulsive and related
disorders (OCRD) were systematically reviewed with the aim of assessing clinical …

Ten years ago deep brain stimulation (DBS) has been introduced as an alternative and
promising treatment option for patients suffering from severe Tourette syndrome (TS). It …

Background Deep brain stimulation (DBS) can be an effective therapy for tics and
comorbidities in select cases of severe, treatment-refractory Tourette syndrome (TS). Clinical …

Fossil records showing trephination in the Stone Age provide evidence that humans have
sought to influence the mind through physical means since before the historical record …

Background: Eighteen patients with severe and refractory Tourette syndrome (TS)
underwent bilateral thalamic deep brain stimulation (DBS). Objective: To assess the long …