[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …

J Boren, MJ Chapman, RM Krauss… - European heart …, 2020 - academic.oup.com
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis

S Zhang, Y Liu, Y Cao, S Zhang, J Sun… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …

Diabetes and ischemic stroke: an old and new relationship an overview of the close interaction between these diseases

CD Maida, M Daidone, G Pacinella, RL Norrito… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus is a comprehensive expression to identify a condition of chronic
hyperglycemia whose causes derive from different metabolic disorders characterized by …

Update on acute coronary syndromes: the pathologists' view

E Falk, M Nakano, JF Bentzon, AV Finn… - European heart …, 2013 - academic.oup.com
Although mortality rates from coronary heart disease in the western countries have declined
in the last few decades, morbidity caused by this disease is increasing and a substantial …

Mechanisms of plaque formation and rupture

JF Bentzon, F Otsuka, R Virmani, E Falk - Circulation research, 2014 - Am Heart Assoc
Atherosclerosis causes clinical disease through luminal narrowing or by precipitating
thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic …

Concept of vulnerable/unstable plaque

AV Finn, M Nakano, J Narula, FD Kolodgie… - … , and vascular biology, 2010 - Am Heart Assoc
Today's concept of vulnerable plaque has evolved primarily from the early pioneering work
uncovering the pivotal role of plaque rupture and coronary thrombosis as the major cause of …

Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome

S Motoyama, M Sarai, H Harigaya, H Anno… - Journal of the American …, 2009 - jacc.org
Objectives: In a computed tomographic (CT) angiography study, we identified the
characteristics of atherosclerotic lesions that were associated with subsequent development …

Pathogenesis of atherosclerosis

E Falk - Journal of the American College of cardiology, 2006 - jacc.org
Atherosclerosis is a multifocal, smoldering, immunoinflammatory disease of medium-sized
and large arteries fuelled by lipids. Endothelial cells, leukocytes, and intimal smooth muscle …

Eruptive calcified nodules as a potential mechanism of acute coronary thrombosis and sudden death

S Torii, Y Sato, F Otsuka, FD Kolodgie… - Journal of the American …, 2021 - jacc.org
Background Calcified nodule (CN) has a unique plaque morphology, in which an area of
nodular calcification causes disruption of the fibrous cap with overlying luminal thrombus …

Vulnerable plaques and patients: state-of-the-art

M Tomaniak, Y Katagiri, R Modolo… - European heart …, 2020 - academic.oup.com
Despite advanced understanding of the biology of atherosclerosis, coronary heart disease
remains the leading cause of death worldwide. Progress has been challenging as half of the …