Background: Antibiotics are essential to effectively treat many hospitalized patients.
However, when antibiotics are prescribed incorrectly, they offer little benefit to patients and …

Background Health care–associated infections (HAIs) are a global health burden because of
their significant impact on patient health and health care systems. Mechanistic simulation …

Background We conducted a systematic review of mathematical models of transmission
dynamic of Clostridium difficile infection (CDI) in healthcare settings, to provide an overview …

Antimicrobial-resistant organisms (AMROs) can colonize people without symptoms for long
periods of time, during which these agents can spread unnoticed to other patients in …

Healthcare-associated infections (HAIs) are a major problem in hospital infection control.
Although HAIs can be suppressed using contact precautions, such precautions are …

To quantify the effect of hospital and community-based transmission and control measures
on Clostridium difficile infection (CDI), we constructed a transmission model within and …

Background Long-term care facilities (LTCFs) are hotspots for pathogen transmission.
Infection control interventions are essential, but the high density and heterogeneity of …

Background Despite intensified efforts to reduce hospital-onset Clostridium difficile infection
(HO-CDI), its clinical and economic impacts continue to worsen. Many institutions have …

Background. Control of Clostridium difficile infection (CDI) is an increasingly difficult problem
for health care institutions. There are commonly recommended strategies to combat CDI …

Following rapid, global clonal dominance of hypervirulent ribotypes, Clostridium difficile now
constitutes the primary infectious cause of nosocomial diarrhoea. Evidence indicates at least …