Effective T cell responses against infections and tumors require a swift and ample production of cytokines, chemokines, and cytotoxic molecules. The production of these …
M Wang, T Ma, H Wang, J Liu, Y Chen… - Nature …, 2021 - nature.com
Precursor messenger RNA (pre-mRNA) splicing is an essential and tightly regulated process in eukaryotic cells; however, the regulatory mechanisms for the splicing are not well …
The genomes of RNA viruses present an astonishing source of both sequence and structural diversity. From intracellular viral RNA-host interfaces to interactions between the RNA …
K Walters, MP Sajek, E Murphy, A Issaian, A Baldwin… - RNA, 2023 - rnajournal.cshlp.org
RNA-binding proteins (RBPs) are key regulators of gene expression. Small molecules targeting these RBP–RNA interactions are a rapidly emerging class of therapeutics for …
HL Cheah, CA Raabe, LP Lee… - Critical Reviews in …, 2018 - Taylor & Francis
Over the past decade, RNA-deep sequencing has uncovered copious non-protein coding RNAs (npcRNAs) in bacteria. Many of them are key players in the regulation of gene …
R Giambruno, J Rupert, E Zacco - Advances in Protein Molecular and …, 2022 - Elsevier
The interactions between proteins and nucleic acids regulate gene expression at transcriptional, post-transcriptional, and translational levels and often dictate the fate of …
Studies in epitranscriptomics indicate that RNA is modified by a variety of enzymes. Among these RNA modifications, adenosine to inosine (A-to-I) RNA editing occurs frequently in the …
M Heim, L Blot, F Besse - STAR protocols, 2022 - Elsevier
RNA-binding proteins (RBPs) are multifunctional proteins that shuttle between the nucleus and the cytoplasm where they assemble with target RNAs to form multi-molecular …
L Cui, D Xing, D Huang, D Li, Q Lu, X Wang… - Biomedicine & …, 2018 - Elsevier
SZNF (Sus scrofa zinc finger CCHC domain containing 3) is a post-transcription regulation factor, belonging to CCHC zinc finger proteins. Cyadox is a novel quinoxaline drug with …