Engineering functional polymer capsules toward smart nanoreactors

J Gaitzsch, X Huang, B Voit - Chemical reviews, 2016 - ACS Publications
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …

Cascade catalysis–strategies and challenges en route to preparative synthetic biology

J Muschiol, C Peters, N Oberleitner… - Chemical …, 2015 - pubs.rsc.org
Nature's smartness and efficient assembling cascade type reactions inspired biologists and
chemists all around the world. Tremendous effort has been directed towards the …

Vesicle-based artificial cells as chemical microreactors with spatially segregated reaction pathways

Y Elani, RV Law, O Ces - Nature communications, 2014 - nature.com
In the discipline of bottom-up synthetic biology, vesicles define the boundaries of artificial
cells and are increasingly being used as biochemical microreactors operating in …

Microfluidic assembly of monodisperse vesosomes as artificial cell models

NN Deng, M Yelleswarapu, L Zheng… - Journal of the American …, 2017 - ACS Publications
Vesosomes are nested liposomal structures with high potential as advanced drug delivery
vehicles, bioreactors and artificial cells. However, to date no method has been reported to …

Multi-enzyme co-immobilized nano-assemblies: Bringing enzymes together for expanding bio-catalysis scope to meet biotechnological challenges

M Bilal, N Hussain, JHP Américo-Pinheiro… - International Journal of …, 2021 - Elsevier
Co-immobilization of multi-enzymes has emerged as a promising concept to design and
signify bio-catalysis engineering. Undoubtedly, the existence and importance of basic …

Engineering compartmentalized biomimetic micro-and nanocontainers

T Trantidou, M Friddin, Y Elani, NJ Brooks, RV Law… - Acs Nano, 2017 - ACS Publications
Compartmentalization of biological content and function is a key architectural feature in
biology, where membrane bound micro-and nanocompartments are used for performing a …

Immobilization of multi-enzymes on support materials for efficient biocatalysis

K Xu, X Chen, R Zheng, Y Zheng - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Multi-enzyme biocatalysis is an important technology to produce many valuable chemicals
in the industry. Different strategies for the construction of multi-enzyme systems have been …

Mimicking cellular compartmentalization in a hierarchical protocell through spontaneous spatial organization

AF Mason, NA Yewdall, PLW Welzen, J Shao… - ACS central …, 2019 - ACS Publications
A systemic feature of eukaryotic cells is the spatial organization of functional components
through compartmentalization. Developing protocells with compartmentalized synthetic …

Biocatalytic self-assembled synthetic vesicles and coacervates: From single compartment to artificial cells

D Gaur, NC Dubey, BP Tripathi - Advances in Colloid and Interface Science, 2022 - Elsevier
Compartmentalization is an intrinsic feature of living cells that allows spatiotemporal control
over the biochemical pathways expressed in them. Over the years, a library of …

[HTML][HTML] Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment

T Einfalt, D Witzigmann, C Edlinger, S Sieber… - Nature …, 2018 - nature.com
Despite tremendous efforts to develop stimuli-responsive enzyme delivery systems, their
efficacy has been mostly limited to in vitro applications. Here we introduce, by using an …