Angiogenin, a well-known angiogenic factor, is crucial to the angiogenesis in
gastrointestinal tumors. Human angiogenin has only one gene, whereas the murine …

In the intestinal tract, where numerous intestinal bacteria reside, intestinal epithelial cells
produce and release various antimicrobial molecules that form a complex barrier on the …

Metformin and pioglitazone monotherapy have been proven to alter gut microbiota in
diabetes and obesity. The present study aimed to investigated whether the combined …

Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic
signals include those provided by mesenchymal cell populations that surround intestinal …

The intestinal epithelium is the first line of host defense, and its homeostasis is dependent
on soluble factors that comprise the crypt niche. Antimicrobial proteins are one of the …

Organisms are now seen as holobionts, consortia of several species that interact
metabolically such that they sustain and scaffold each other's existence and propagation …

Introduction: Aging studies in humans and mice have played a key role in understanding the
intestinal microbiome and an increased abundance of “inflammaging” Gram-negative (Gn) …

Gut disorders, like inflammatory bowel disease, are becoming increasingly common. To
develop better treatments, we need to understand how the gut works and what happens at …