Pharmacogenetics guidelines: overview and comparison of the DPWG, CPIC, CPNDS, and RNPGx guidelines

H Abdullah-Koolmees, AM Van Keulen… - Frontiers in …, 2021 - frontiersin.org
Many studies have shown that the efficacy and risk of side effects of drug treatment is
influenced by genetic variants. Evidence based guidelines are essential for implementing …

The genetics of bipolar disorder

FJA Gordovez, FJ McMahon - Molecular psychiatry, 2020 - nature.com
Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …

Practical guidance for the evaluation and management of drug hypersensitivity: specific drugs

AD Broyles, A Banerji, S Barmettler, CM Biggs… - The Journal of Allergy …, 2020 - Elsevier
Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

The management of epilepsy in children and adults

P Perucca, IE Scheffer, M Kiley - Medical Journal of Australia, 2018 - Wiley Online Library
Summary The International League Against Epilepsy has recently published a new
classification of epileptic seizures and epilepsies to reflect the major scientific advances in …

[PDF][PDF] Spanish guidelines for diagnosis, management, treatment, and prevention of DRESS syndrome

R Cabañas, E Ramírez, E Sendagorta… - J Investig Allergol …, 2020 - researchgate.net
Symptoms) is a complex multisystemic severe drug hypersensitivity reaction whose
diagnosis and management are troublesome. It involves the management by different …

Epilepsy and brain tumors

DJ Englot, EF Chang, CJ Vecht - Handbook of clinical neurology, 2016 - Elsevier
Seizures are common in patients with brain tumors, and epilepsy can significantly impact
patient quality of life. Therefore, a thorough understanding of rates and predictors of …

Recommendations for genetic testing to reduce the incidence of anthracycline‐induced cardiotoxicity

F Aminkeng, CJD Ross, SR Rassekh… - British journal of …, 2016 - Wiley Online Library
Aims Anthracycline‐induced cardiotoxicity (ACT) occurs in 57% of treated patients and
remains an important limitation of anthracycline‐based chemotherapy. In various genetic …

SJS/TEN 2017: building multidisciplinary networks to drive science and translation

KD White, R Abe, M Ardern-Jones… - The Journal of Allergy …, 2018 - Elsevier
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening,
immunologically mediated, and usually drug-induced disease with a high burden to …

Physician-reported benefits and barriers to clinical implementation of genomic medicine: a multi-site IGNITE-network survey

A Owusu Obeng, K Fei, KD Levy, AR Elsey… - Journal of personalized …, 2018 - mdpi.com
Genetic medicine is one of the key components of personalized medicine, but adoption in
clinical practice is still limited. To understand potential barriers and provider attitudes, we …

[HTML][HTML] Recent advances in managing and understanding Stevens-Johnson syndrome and toxic epidermal necrolysis

A Hasegawa, R Abe - F1000Research, 2020 - ncbi.nlm.nih.gov
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
diseases characterized by detachment of the epidermis and mucous membrane. SJS/TEN …