The physics of radioembolization
R Bastiaannet, SC Kappadath, B Kunnen, AJAT Braat… - EJNMMI physics, 2018 - Springer
Radioembolization is an established treatment for chemoresistant and unresectable liver
cancers. Currently, treatment planning is often based on semi-empirical methods, which …
cancers. Currently, treatment planning is often based on semi-empirical methods, which …
ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …
inception in 1925, has had as its principal objective the development of internationally …
Radioembolization dosimetry: the road ahead
Methods for calculating the activity to be administered during yttrium-90 radioembolization
(RE) are largely based on empirical toxicity and efficacy analyses, rather than dosimetry. At …
(RE) are largely based on empirical toxicity and efficacy analyses, rather than dosimetry. At …
The superior predictive value of 166Ho-scout compared with 99mTc-macroaggregated albumin prior to 166Ho-microspheres radioembolization in patients with liver …
Purpose As an alternative to technetium-99m-macroaggregated albumin (99m Tc-MAA), a
scout dose of holmium-166 (166 Ho) microspheres can be used prior to 166 Ho …
scout dose of holmium-166 (166 Ho) microspheres can be used prior to 166 Ho …
Efficacy of radioembolization with 166Ho-microspheres in salvage patients with liver metastases: a phase 2 study
JF Prince, MAAJ van den Bosch… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Radioembolization of liver malignancies with 166Ho-microspheres has been shown to be
safe in a phase 1 dose-escalation study. The purpose of this study was to investigate the …
safe in a phase 1 dose-escalation study. The purpose of this study was to investigate the …
99mTc-MAA overestimates the absorbed dose to the lungs in radioembolization: a quantitative evaluation in patients treated with 166Ho-microspheres
Purpose Radiation pneumonitis is a rare but serious complication of radioembolic therapy of
liver tumours. Estimation of the mean absorbed dose to the lungs based on pretreatment …
liver tumours. Estimation of the mean absorbed dose to the lungs based on pretreatment …
Safety analysis of holmium-166 microsphere scout dose imaging during radioembolisation work-up: a cohort study
Objective Radioembolisation is generally preceded by a scout dose of technetium-99m-
macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 …
macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 …
First evidence for a dose–response relationship in patients treated with 166Ho radioembolization: a prospective study
R Bastiaannet, C van Roekel, MLJ Smits… - Journal of Nuclear …, 2020 - Soc Nuclear Med
166Ho-microspheres have recently been approved for clinical use for hepatic
radioembolization in the European Union. The aim of this study was to investigate the …
radioembolization in the European Union. The aim of this study was to investigate the …
Accelerated SPECT image reconstruction with FBP and an image enhancement convolutional neural network
MMA Dietze, W Branderhorst, B Kunnen, MA Viergever… - EJNMMI physics, 2019 - Springer
Abstract Background Monte Carlo-based iterative reconstruction to correct for photon scatter
and collimator effects has been proven to be superior over analytical correction schemes in …
and collimator effects has been proven to be superior over analytical correction schemes in …
Additional hepatic 166Ho-radioembolization in patients with neuroendocrine tumours treated with 177Lu-DOTATATE; a single center, interventional, non …
AJAT Braat, DJ Kwekkeboom, BLR Kam… - BMC …, 2018 - Springer
Background Neuroendocrine tumours (NET) consist of a heterogeneous group of
neoplasms with various organs of origin. At diagnosis 21% of the patients with a Grade 1 …
neoplasms with various organs of origin. At diagnosis 21% of the patients with a Grade 1 …