Role of tau protein in Alzheimer's disease: The prime pathological player

S Muralidar, SV Ambi, S Sekaran, D Thirumalai… - International journal of …, 2020 - Elsevier
Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …

Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Surface plasmon resonance biosensors for detection of Alzheimer's biomarkers; an effective step in early and accurate diagnosis

A Rezabakhsh, R Rahbarghazi, F Fathi - Biosensors and Bioelectronics, 2020 - Elsevier
The rapid and direct detection of biomarkers in biofluids at clinically relevant concentrations
faces serious limitations to develop diagnostic criteria for neurodegenerative diseases such …

Microbial involvement in Alzheimer disease development and progression

HR Bulgart, EW Neczypor, LE Wold… - Molecular …, 2020 - Springer
Alzheimer disease (AD) is the most prominent form of dementia and the 5th leading cause of
death in individuals over 65. AD is a complex disease stemming from genetic …

Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review

Z Haghighijoo, L Zamani, F Moosavi… - European journal of …, 2022 - Elsevier
Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

The roles of the amyloid beta monomers in physiological and pathological conditions

TG Schreiner, OD Schreiner, M Adam, BO Popescu - Biomedicines, 2023 - mdpi.com
Amyloid beta peptide is an important biomarker in Alzheimer's disease, with the
amyloidogenic hypothesis as one of the central hypotheses trying to explain this type of …

The brilliance of the zebrafish model: perception on behavior and Alzheimer's disease

A Shenoy, M Banerjee, A Upadhya… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) has become increasingly prevalent in the elderly population
across the world. It's pathophysiological markers such as overproduction along with the …

Role of withaferin A and its derivatives in the management of Alzheimer's disease: Recent trends and future perspectives

R Das, A Rauf, S Akhter, MN Islam, TB Emran, S Mitra… - Molecules, 2021 - mdpi.com
Globally, Alzheimer's disease (AD) is one of the most prevalent age-related
neurodegenerative disorders associated with cognitive decline and memory deficits due to …

Amyloid β peptide promotes bone formation by regulating Wnt/β‐catenin signaling and the OPG/RANKL/RANK system

B Yang, S Li, Z Chen, F Feng, L He, B Liu… - The FASEB …, 2020 - Wiley Online Library
Background Amyloid β peptide (Aβ) is involved in osteoporosis, but the effects of Aβ on
osteoblast and bone formation remain unclear. In this study, we investigated the effect of Aβ …

The role of dietary antioxidants in the pathogenesis of neurodegenerative diseases and their impact on cerebral oxidoreductive balance

A Winiarska-Mieczan, E Baranowska-Wójcik… - Nutrients, 2020 - mdpi.com
Neurodegenerative diseases are progressive diseases of the nervous system that lead to
neuron loss or functional disorders. Neurodegenerative diseases require long-term …