Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian brain has evolved a unique mechanism for CBF control known as neurovascular coupling …
PJ Drew - Trends in neurosciences, 2022 - cell.com
In the brain, increases in neural activity drive changes in local blood flow via neurovascular coupling. The common explanation for increased blood flow (known as functional …
EMC Hillman - Annual review of neuroscience, 2014 - annualreviews.org
Functional magnetic resonance imaging (fMRI) provides a unique view of the working human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …
Neuronal activity results in increased blood flow in the brain, a response named functional hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
Recent developments in the area of biological detection by optical sensing of molecular oxygen (O2) are reviewed, with particular emphasis on the quenched-phosphorescence O2 …
AY Shih, JD Driscoll, PJ Drew… - Journal of Cerebral …, 2012 - journals.sagepub.com
The cerebral vascular system services the constant demand for energy during neuronal activity in the brain. Attempts to delineate the logic of neurovascular coupling have been …
IG Gould, P Tsai, D Kleinfeld… - Journal of Cerebral …, 2017 - journals.sagepub.com
The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …
RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic patterns of activity in the working human brain. Although the initial discoveries that led to …
The microvasculature underlies the supply networks that support neuronal activity within heterogeneous brain regions. What are common versus heterogeneous aspects of the …