Biocatalysts represent an efficient, highly selective and greener alternative to metal catalysts in both industry and academia. In the last two decades, the interest in biocatalytic …
Z Wang, BS Sekar, Z Li - Bioresource Technology, 2021 - Elsevier
Enzyme cascades are efficient tools to perform multi-step synthesis in one-pot in a green and sustainable manner, enabling non-natural synthesis of valuable chemicals from easily …
The use of magnetic biocatalysts is highly beneficial in bioprocesses technology, as it allows their easy recovering and enhances biocatalyst lifetime. Thus, it simplifies operational …
Conspectus Molecules containing carbohydrate moieties play essential roles in fighting a variety of bacterial and viral infections. Consequently, the design of new carbohydrate …
SC Cosgrove, GJ Miller - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Nucleoside analogues represent a cornerstone of achievement in drug discovery, rising to prominence particularly in the fields of antiviral and anticancer discovery …
Nucleosides are ubiquitous to life and are required for the synthesis of DNA, RNA, and other molecules crucial for cell survival. Despite the notoriously difficult organic synthesis of …
Nucleoside phosphorylases have progressed from an enzymatic curiosity to a viable synthetic tool. However, despite the recent advances in nucleoside phosphorylase …
AI Benítez‐Mateos, F Paradisi - ChemSusChem, 2022 - Wiley Online Library
The continuous synthesis of valuable nucleoside drugs was achieved in up to 99% conversion by using a novel halotolerant purine nucleoside phosphorylase from Halomonas …
Simvastatin is a top-selling cholesterol-lowering drug traditionally obtained through a semi- synthetic process starting from lovastatin. However, this process is cost-demanding and …