Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …

Ulcerative colitis (UC) is a chronic recurrent intestinal inflammatory disease characterized by
high incidence and young onset age. Recently, there have been some interesting findings in …

Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

The first rudimentary evidence that the human body harbors a microbiota hinted at the
complexity of host-associated microbial ecosystems. Now, almost 400 years later, a …

Mucus is integral to gut health and its properties may be affected in neurological disease.
Mucus comprises a hydrated network of polymers including glycosylated mucin proteins. We …

The normal intestinal microbiota inhabits the colon mucus without triggering an inflammatory
response. The reason for this and how the intestinal mucus of the colon is organized have …

Mammals and their intestinal microbiota peacefully coexist in a mutualistic relationship.
Commensal bacteria play an active role in shaping and modulating physiological processes …

Genomic technologies have significantly advanced our understanding of the composition
and diversity of host-associated microbial populations. However, their spatial organization …

High mucosal and fecal concentrations of the antimicrobial siderophore-binding peptide
Lipocalin-2 (Lcn2) are observed in inflammatory bowel disease. However, Lcn2 function in …

The distal human gut is a microbial bioreactor that digests complex carbohydrates. The
strategies evolved by gut microbes to sense and process diverse glycans have important …