KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

[HTML][HTML] Intensive supportive care plus immunosuppression in IgA nephropathy

T Rauen, F Eitner, C Fitzner, C Sommerer… - … England Journal of …, 2015 - Mass Medical Soc
Background The outcomes of immunosuppressive therapy, when added to supportive care,
in patients with IgA nephropathy are uncertain. Methods We conducted a multicenter, open …

IgA nephropathy in children and in adults: two separate entities or the same disease?

R Coppo, T Robert - Journal of Nephrology, 2020 - Springer
IgA nephropathy (IgAN) is observed in subjects of any age, however perspective and
management of this disease are different between adult and pediatrician Nephrologists …

Clinical and histological risk factors for progression of IgA nephropathy: an update in children, young and adult patients

R Coppo - Journal of nephrology, 2017 - Springer
The identification of risk factors conditioning the progression of immunoglobulin (Ig) A
nephropathy (IgAN) is needed due to the variability of the outcome of this renal disease …

Risk factors for progression in children and young adults with IgA nephropathy: an analysis of 261 cases from the VALIGA European cohort

R Coppo, D Lofaro, RR Camilla, S Bellur, D Cattran… - Pediatric …, 2017 - Springer
Background There is a need for early identification of children with immunoglobulin A
nephropathy (IgAN) at risk of progression of kidney disease. Methods Data on 261 young …

Corticosteroids in IgA nephropathy: lessons from recent studies

R Coppo - Journal of the American Society of Nephrology, 2017 - journals.lww.com
IgA nephropathy (IgAN) is a common chronic glomerular disease that, in most patients,
slowly progresses to ESRD. The immune and autoimmune responses that characterize IgAN …

Updating the international IgA nephropathy prediction tool for use in children

SJ Barbour, R Coppo, L Er, ML Russo, ZH Liu, J Ding… - Kidney International, 2021 - Elsevier
Although IgA nephropathy (IgAN) is a common cause of glomerulonephritis in children, the
absence of a method to predict disease progression limits personalized risk-based treatment …

Toll-like receptors, immunoproteasome and regulatory T cells in children with Henoch–Schönlein purpura and primary IgA nephropathy

ME Donadio, E Loiacono, L Peruzzi, A Amore… - Pediatric …, 2014 - Springer
Abstract Background Henoch–Schönlein purpura (HSP) nephritis and primary IgA
nephropathy (pIgAN) present with glomerular IgA deposits, but differ with regard to clinical …

Biomarkers and targeted new therapies for IgA nephropathy

R Coppo - Pediatric Nephrology, 2017 - Springer
IgA nephropathy (IgAN) has variable clinical presentation and outcome. There is a need to
identify children who have the potential to progress to end stage renal disease (ESRD) …

[HTML][HTML] Immunosuppressive treatment in children with IgA nephropathy and the clinical value of podocytopathic features

A Cambier, M Rabant, M Peuchmaur, A Hertig… - Kidney International …, 2018 - Elsevier
Introduction There is a need for treatment guidelines and prognostic factor identification in
children with primary IgA nephropathy. We analyzed the causative effect of steroids and the …