MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact

G Evangelatos, GE Fragoulis, V Koulouri… - Autoimmunity reviews, 2019 - Elsevier
Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

The therapeutic and diagnostic role of exosomes in cardiovascular diseases

P Zamani, N Fereydouni, AE Butler… - Trends in cardiovascular …, 2019 - Elsevier
Exosomes are nano-sized membranous vesicles that are secreted by cells. They have an
important role in transferring proteins, mRNA, miRNA and other bioactive molecules …

Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets

H Long, X Wang, Y Chen, L Wang, M Zhao, Q Lu - Cancer letters, 2018 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

Exosomes: Effectual players in rheumatoid arthritis

F Tavasolian, AS Moghaddam, F Rohani… - Autoimmunity …, 2020 - Elsevier
Rheumatoid arthritis is a well-known chronic inflammatory joint disorder. It encompasses
systemic inflammation, autoimmunity and development of several joint abnormalities leading …

MiR‐548a‐3p regulates inflammatory response via TLR4/NF‐κB signaling pathway in rheumatoid arthritis

Y Wang, F Zheng, G Gao, S Yan… - Journal of cellular …, 2019 - Wiley Online Library
Currently published studies have implicated that microRNAs (miRNAs) including exosomes‐
encapsulated miRNAs play a critical role in rheumatoid arthritis (RA). Previously, we have …

Role of miRNAs in rheumatoid arthritis therapy

Y Zhang, M Yang, H Xie, F Hong, S Yang - Cells, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by
autoimmunity, synovial inflammation and joint destruction. Pannus formation in the synovial …

Role of microRNA shuttled in small extracellular vesicles derived from mesenchymal stem/stromal cells for osteoarticular disease treatment

E Lara-Barba, MJ Araya, CN Hill… - Frontiers in …, 2021 - frontiersin.org
Osteoarticular diseases (OD), such as rheumatoid arthritis (RA) and osteoarthritis (OA) are
chronic autoimmune/inflammatory and age-related diseases that affect the joints and other …

Epigenetics of inflammatory arthritis

D Hammaker, GS Firestein - Current opinion in rheumatology, 2018 - journals.lww.com
Epigenetics of inflammatory arthritis : Current Opinion in Rheumatology Epigenetics of
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