Heterocyclic naphthalimides as new skeleton structure of compounds with increasingly expanding relational medicinal applications

HH Gong, D Addla, JS Lv… - Current topics in medicinal …, 2016 - ingentaconnect.com
Naphthalimide compounds are an important type of nitrogen-containing aromatic
heterocycles with cyclic double imides and the naphthalene framework. This π-deficient …

Solvent-dependent chromogenic sensing for Cu2+ and fluorogenic sensing for Zn2+ and Al3+: a multifunctional chemosensor with dual-mode

GJ Park, DY Park, KM Park, Y Kim, SJ Kim, PS Chang… - Tetrahedron, 2014 - Elsevier
A new multifunctional chemosensor 1 was synthesized and characterized by spectroscopic
tools along with a single crystal X-ray crystallography. It can exhibit selective recognition …

A single chemosensor for multiple analytes: fluorogenic detection of Zn 2+ and OAc− ions in aqueous solution, and an application to bioimaging

GJ Park, YJ Na, HY Jo, SA Lee, AR Kim, I Noh… - New Journal of …, 2014 - pubs.rsc.org
A new highly selective and sensitive chemosensor 1 for both Zn2+ and OAc− with off–on
fluorescence behavior in aqueous solution was developed. The selectivity mechanism of 1 …

A turn-on and reversible fluorescence sensor with high affinity to Zn2+ in aqueous solution

GJ Park, MM Lee, GR You, YW Choi, C Kim - Tetrahedron Letters, 2014 - Elsevier
A new simple receptor 1 based on aminosalicylimine was prepared. It exhibited an 'off–on
fluorescence type'mode with high sensitivity in the presence of Zn 2+. In particular, this …

Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors

A Prandina, S Radix, M Le Borgne, LP Jordheim… - Tetrahedron, 2019 - Elsevier
Antibiotics are key drugs in modern healthcare, especially in hospitals, where multiresistant
bacteria resides and is a potential threat to human health. In the present work, a new series …

Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors

G Kildahl-Andersen, C Schnaars, A Prandina… - …, 2019 - pubs.rsc.org
The syntheses of metallo-β-lactamase inhibitors comprising chelating moieties, with varying
zinc affinities, and peptides partly inspired from bacterial peptide sequences, have been …

A new turn-on fluorescence probe for Zn2+ in aqueous solution and imaging application in living cells

MM Li, FW Wang, XY Wang, TT Zhang, Y Xu… - Analytica Chimica …, 2014 - Elsevier
We designed and synthesized a new pyrazoline-based turn-on fluorescence probe for Zn 2+
by the reaction of chalcone and thiosemicarbazide. The structure of the probe was …

A simple pincer-type chemosensor for reversible fluorescence turn-on detection of zinc ion at physiological pH range

Q Lin, Y Cai, Q Li, J Chang, H Yao, YM Zhang… - New Journal of …, 2015 - pubs.rsc.org
A new, highly selective and sensitive pincer-type chemosensor (Y) for zinc ion with turn-on
fluorescence behavior in physiological pH range solution was developed. Y is based on bi …

Progressive structural modification to a zinc-actuated photoinduced electron transfer (PeT) switch in the context of intracellular zinc imaging

M Macias-Contreras, KL Daykin, JT Simmons… - Organic & …, 2017 - pubs.rsc.org
Photoinduced electron transfer (PeT)-type fluorescent molecular switches are often applied
in ion-selective sensors. Zinc-targeting sensors that contain an anilino-based electron donor …

Inhibitors of metallo-beta-lactamase (MBL) comprising a zinc chelating moiety

P Rongved, OAH Åstrand, A Bayer, HS Leiros… - US Patent …, 2019 - Google Patents
A61K 45/06 A61P 31/04 wherein A represents a lipophilic chelating moiety which is
selective for Zn2+ ions; L is a covalent bond or a linker; and B is a vector which is either a …