Biology capitalizes on the specific chemistries of certain transition metal ions. In fact, life
depends on transition metal ions as essential trace elements. Biological redox processes …

Asymmetric (NG, NG)-dimethylarginine (ADMA) inhibits nitric oxide (NO) synthases (NOS).
ADMA is a risk factor for endothelial dysfunction, cardiovascular mortality, and progression …

Asymmetric dimethylarginine (ADMA) is synthesized during the methylation of protein
arginine residues by protein arginine methyltransferases (PRMT) and is released during …

Asymmetric dimethylarginine (ADMA)—a naturally occurring amino acid that is a product of
protein breakdown—is released into the cytoplasm following the post-translational …

The asymmetric methylarginines inhibit nitric oxide synthesis in vivo by competing with L-
arginine at the active site of nitric oxide synthase. High circulating levels of asymmetric …

The understanding of nitric oxide (NO) signaling has grown substantially since the
identification of endothelial derived relaxing factor (EDRF). NO has emerged as a ubiquitous …

The small free radical gas nitric oxide (NO) plays a key role in various physiological and
pathological processes through enhancement of endothelial cell survival and proliferation …

S-nitrosylation, the covalent attachment of a nitric oxide to (NO) the sulfur atom of cysteine, is
a selective and reversible protein post-translational modification (PTM) that regulates protein …

Mass spectrometry (MS) has become a powerful and widely utilized tool in the investigation
of protein thiol chemistry, biochemistry, and biology. Very early biochemical studies of …

NO participates in numerous biological events in a variety of cell types including activated
glomerular mesangial cells. Many of these events appear to be independent of the known …